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Phenylethyl glycol

Updated: 2026-08-28

Overview

Phenaglycodol, chemically known as 2-(p-Chlorophenyl)-3-methyl-2,3-butanediol, is a synthetic compound that was historically used as a central nervous system depressant and muscle relaxant. It gained prominence in the mid-20th century for its sedative effects but has since seen reduced use due to the development of newer pharmaceuticals with fewer side effects. Despite its decline in medical applications, Phenaglycodol remains of interest in chemical research and historical pharmaceutical studies. Its synthesis and properties are well-documented, making it a reference compound in certain academic and industrial contexts.

Physical and Chemical Properties

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Phenaglycodol is a white crystalline powder with a molecular weight of 214.69 g/mol. It has a melting point of approximately 105-107°C and is slightly soluble in water, though it dissolves more readily in organic solvents like ethanol and ether. These properties make it suitable for various formulation processes in pharmaceutical applications. The compound's stability under normal storage conditions is moderate, but it should be protected from light and moisture to prevent degradation. Its molecular structure includes a chlorophenyl group, which contributes to its biological activity and solubility characteristics.

Main Applications

Historically, Phenaglycodol was primarily used as a sedative and muscle relaxant in clinical settings. It was prescribed to alleviate anxiety and tension, as well as to manage certain neuromuscular conditions. However, its use has declined due to the availability of more effective and safer alternatives. Today, Phenaglycodol is mainly utilized in research settings, particularly in studies exploring the development and effects of central nervous system depressants. It serves as a reference compound for understanding the pharmacological profiles of similar substances.

Safety and Storage

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Phenaglycodol should be handled with care due to its potential to cause drowsiness or dizziness. Prolonged exposure or misuse can lead to central nervous system depression, necessitating proper safety measures during handling and storage. For optimal preservation, the compound should be stored in a cool, dry place, away from direct light and moisture. Containers should be tightly sealed to prevent contamination and degradation. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines.

B2B Procurement Guide

When procuring Phenaglycodol, B2B buyers should prioritize suppliers with verified credentials and compliance with regulatory standards. Purity and quality certifications are essential to ensure the compound meets the required specifications for its intended use. Prices can vary significantly based on purity levels and supplier terms, so obtaining multiple quotes is advisable. Buyers should also confirm the availability of technical support and documentation, such as certificates of analysis (CoA), to facilitate smooth transactions and applications.

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