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Phenylcyclopentane

Updated: 2026-08-06

Overview

Phenylcyclopentane, also known as cyclopentylbenzene, is an organic compound with the molecular formula C11H14. It is a colorless to pale yellow liquid with a characteristic aromatic odor. The compound is primarily used as an intermediate in the synthesis of pharmaceuticals, fragrances, and other specialty chemicals. Due to its stable cycloalkane structure, phenylcyclopentane serves as a versatile building block in organic chemistry. It is insoluble in water but readily dissolves in common organic solvents such as ethanol, ether, and acetone. Industrial production typically involves catalytic hydrogenation or Friedel-Crafts alkylation processes.

Physical and Chemical Properties

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Phenylcyclopentane exhibits typical properties of aromatic hydrocarbons. It has a boiling point range of 190-195°C and a melting point around -50°C, making it a liquid at room temperature. The compound's density is approximately 0.93 g/cm³, slightly less than water. The cyclopentyl group attached to the benzene ring provides moderate reactivity in chemical transformations. Phenylcyclopentane is relatively stable under normal conditions but can undergo electrophilic aromatic substitution reactions. Its volatility requires proper handling to prevent evaporation losses in industrial applications.

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Main Applications

In the pharmaceutical industry, phenylcyclopentane serves as a precursor for various active pharmaceutical ingredients (APIs). Its structure makes it valuable for synthesizing compounds with central nervous system activity. The fragrance industry utilizes phenylcyclopentane as a building block for musky and woody scent compounds. When properly derivatized, it contributes to long-lasting fragrance formulations in perfumes and personal care products. Additional applications include use as a specialty solvent in certain industrial processes and as a standard in analytical chemistry for calibration purposes.

Safety and Storage

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As a flammable organic compound, phenylcyclopentane requires careful handling. Storage should be in tightly sealed containers away from heat sources and open flames. Proper grounding is essential during transfer to prevent static electricity buildup. Personal protective equipment including chemical-resistant gloves and eye protection should be worn when handling. In case of skin contact, wash immediately with soap and water. The compound may cause irritation to respiratory system - adequate ventilation or respiratory protection is recommended for large-scale operations.

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B2B Procurement Guide

When procuring phenylcyclopentane, verify the supplier's ability to provide consistent quality and documentation. Key documents include Certificate of Analysis (COA) and Safety Data Sheet (SDS). Consider purity requirements for your specific application - technical grade (90-95%) is typically sufficient for industrial use, while higher purity (98%+) may be needed for pharmaceutical applications. Bulk purchases (drum quantities) generally offer better pricing, but evaluate storage capacity and usage rate to avoid material degradation over time.

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