Overview
Phenylanthranilic acid, chemically known as 2-anilinobenzoic acid, is an organic compound with significant applications in pharmaceuticals and chemical synthesis. It is derived from the reaction of anthranilic acid with aniline. The compound is valued for its role as an intermediate in the production of various drugs and dyes. Its molecular structure includes both an aromatic ring and a carboxylic acid group, making it versatile for further chemical modifications. The compound is typically available as a white crystalline powder, which is stable under standard conditions but should be handled with care to avoid exposure.
Physical and Chemical Properties
Phenylanthranilic acid exhibits a melting point range of 180-183°C, indicating its stability at moderate temperatures. It is soluble in common organic solvents such as ethanol and acetone, but its solubility in water is limited. This property makes it suitable for reactions in non-aqueous media. The compound's weak acidic nature allows it to participate in reactions typical of carboxylic acids, such as esterification and amide formation. Its aromatic ring structure also enables electrophilic substitution reactions, broadening its utility in synthetic chemistry. The crystalline form ensures easy handling and storage, though moisture should be avoided to prevent degradation.
Main Applications
Phenylanthranilic acid is primarily used as an intermediate in the pharmaceutical industry, where it contributes to the synthesis of active pharmaceutical ingredients (APIs). Its derivatives are found in medications targeting inflammation and pain relief. In the dye industry, the compound serves as a precursor for azo dyes, which are widely used in textiles and printing. Additionally, it is employed in chemical research as a reagent for studying reaction mechanisms and developing new synthetic pathways. Its versatility and reliability make it a staple in industrial and laboratory settings.
Safety and Storage
Handling phenylanthranilic acid requires adherence to safety protocols to minimize health risks. Direct contact with skin or eyes can cause irritation, and inhalation of dust should be avoided. Personal protective equipment (PPE), including gloves and goggles, is recommended during use. Storage conditions should prioritize cool, dry environments to maintain the compound's stability. Containers must be tightly sealed to prevent moisture absorption and contamination. In case of spills, neutralization with a mild base and proper disposal procedures should be followed to ensure environmental safety.
B2B Procurement Guide
When procuring phenylanthranilic acid, buyers should prioritize suppliers with verified certifications and a track record of quality assurance. Key specifications to confirm include CAS number (91-40-7) and purity levels, which typically range from 98% to 99.5%. Price negotiations should consider bulk purchase discounts, with reference prices commonly between $50 and $150 per kilogram. Logistics planning should account for the compound's stability, ensuring transportation conditions prevent exposure to extreme temperatures or humidity. Establishing long-term supplier relationships can secure consistent quality and reliable delivery schedules.
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