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Phenoxyethanol

Updated: 2026-08-06

Overview

Phenoxyethanol is an organic compound belonging to the glycol ether family, widely recognized for its preservative and solvent properties. It is synthesized through the reaction between phenol and ethylene oxide. Due to its efficacy against bacteria, fungi, and yeast, it is a preferred ingredient in personal care products, pharmaceuticals, and industrial formulations. The compound's stability and low toxicity profile make it suitable for long-term use in aqueous solutions. Its mild rose-like odor and compatibility with various ingredients further enhance its utility in cosmetic and pharmaceutical applications.

Physical and Chemical Properties

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Phenoxyethanol is a colorless to pale yellow liquid with a faint aromatic odor. It exhibits moderate volatility and is miscible with water, alcohols, and many organic solvents. Its boiling point of 245°C ensures stability under typical processing conditions. The compound's antimicrobial action is attributed to its ability to disrupt microbial cell membranes. Its chemical stability in acidic and neutral pH ranges makes it versatile for formulations requiring long shelf lives. However, it may degrade under strong alkaline conditions or prolonged UV exposure.

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Main Applications

In cosmetics, phenoxyethanol is a common preservative in creams, lotions, and shampoos, often used at concentrations of 0.5-1%. It is also found in vaccines and injectable medications as a stabilizer. Industrial applications include its use as a solvent for dyes, inks, and resins. Its low volatility and high solvency power make it ideal for slow-drying formulations. Additionally, it serves as a fixative in perfumery to prolong fragrance longevity.

Safety and Storage

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Phenoxyethanol is generally regarded as safe when used within recommended concentrations. However, prolonged skin contact may cause irritation, and inhalation of vapors should be avoided. Proper storage involves keeping containers tightly sealed in a cool, ventilated area away from oxidizing agents. Regulatory bodies such as the FDA and EU Cosmetics Regulation permit its use up to 1% in leave-on products. Safety Data Sheets (SDS) should be consulted for handling and disposal guidelines to ensure workplace compliance.

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B2B Procurement Guide

Industrial buyers should prioritize suppliers who provide Certificates of Analysis (CoA) detailing purity, heavy metal content, and microbial limits. Bulk purchases (e.g., 200 kg drums) often reduce unit costs but require verification of storage compatibility. Key procurement considerations include regulatory compliance (e.g., REACH, FDA 21 CFR), packaging options (HDPE drums or IBC totes), and logistics for hazardous material transport. Sample testing is recommended to confirm suitability for specific formulations.

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