Overview
Pharmaceutical Grade Antipyrine, also known as Phenazone, is a synthetic compound widely used in the medical field for its analgesic and antipyretic properties. It was first synthesized in the late 19th century and has since become a staple in pain relief and fever reduction medications. Its chemical stability and efficacy make it a preferred choice in pharmaceutical formulations. Antipyrine is classified as a non-opioid analgesic, meaning it does not interact with the central nervous system in the same way as opioids. This makes it a safer alternative for managing mild to moderate pain and fever, particularly in patients who cannot tolerate opioids or other stronger analgesics.
Physical and Chemical Properties
Pharmaceutical Grade Antipyrine is a white crystalline powder with a molecular weight of 188.23 g/mol. It has a melting point range of 110-113°C and a boiling point of 319°C. The compound is soluble in water, alcohol, and chloroform, which facilitates its incorporation into various pharmaceutical formulations. The density of Antipyrine is approximately 1.19 g/cm³, and it exhibits stability under normal storage conditions. Its chemical structure includes a pyrazole ring, which contributes to its pharmacological activity. The compound is known for its relatively low toxicity, making it suitable for widespread medical use.
Main Applications
The primary application of Pharmaceutical Grade Antipyrine is in the formulation of analgesic and antipyretic medications. It is commonly found in over-the-counter pain relievers and fever reducers, often combined with other active ingredients to enhance efficacy. Antipyrine is also used in veterinary medicine for similar purposes. In addition to its medical uses, Antipyrine is employed in research laboratories as a reference standard for pharmacological studies. Its well-documented properties and consistent performance make it a reliable tool for scientific investigations into pain and fever mechanisms.
Safety and Storage
While Pharmaceutical Grade Antipyrine is generally safe for use, proper handling and storage are essential to maintain its integrity and prevent adverse effects. The compound should be stored in a cool, dry place, away from direct light and moisture to avoid degradation. Safety precautions include wearing protective gloves and eyewear when handling the powder to prevent skin and eye irritation. In case of accidental ingestion or exposure, seek medical attention immediately. It is also important to ensure that the compound is kept out of reach of children and pets.
B2B Procurement Guide
When procuring Pharmaceutical Grade Antipyrine, it is crucial to source from reputable suppliers who comply with pharmaceutical standards and certifications. Key considerations include the purity of the compound, which should meet or exceed pharmacopeial specifications such as USP or EP standards. Buyers should also verify the supplier's documentation, including certificates of analysis (CoA) and material safety data sheets (MSDS). Pricing can vary based on purity and order quantity, with typical reference prices ranging from $50 to $100 per kg. Bulk purchases may offer cost savings, but quality should never be compromised for price.
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