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Pentadecapeptide

Updated: 2026-08-05

Overview

Pentadecapeptide is a synthetic peptide chain consisting of 15 amino acids. It is designed for specific biological activities, particularly in skincare and therapeutic applications. Due to its customizable sequence, it can target various skin concerns such as wrinkles, elasticity loss, and hydration. In the B2B sector, pentadecapeptide is primarily supplied to cosmetic manufacturers and pharmaceutical companies. Its efficacy in promoting collagen synthesis and cell regeneration makes it a valuable ingredient in anti-aging formulations. The peptide is typically synthesized using solid-phase peptide synthesis (SPPS) to ensure high purity and consistency.

Physical and Chemical Properties

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Pentadecapeptide appears as a white to off-white powder, with solubility in water and select organic solvents. Its molecular weight ranges between 1500-2000 g/mol, depending on the amino acid sequence. The peptide is stable under recommended storage conditions but may degrade if exposed to extreme temperatures or humidity. Key chemical properties include its ability to interact with skin receptors to stimulate collagen production. The peptide’s bioactivity is highly sequence-dependent, requiring precise synthesis and handling. Analytical techniques such as HPLC and mass spectrometry are used to verify purity and sequence accuracy during quality control.

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Main Applications

The primary application of pentadecapeptide is in the cosmetics industry, where it is incorporated into serums, creams, and lotions for its anti-aging benefits. It works by mimicking natural skin signals to enhance collagen and elastin production, reducing visible wrinkles and improving skin texture. In pharmaceuticals, pentadecapeptide is explored for wound healing and tissue regeneration. Its bioactive properties make it a candidate for dermatological treatments. Additionally, research is ongoing into its potential use in nutraceuticals for skin health supplements. B2B buyers should ensure compatibility with their formulation requirements, including pH stability and synergy with other ingredients.

Safety and Storage

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Pentadecapeptide is generally safe for topical use when formulated correctly. However, raw peptide powder should be handled with care to avoid inhalation or eye contact. Personal protective equipment (PPE) such as gloves and masks is recommended during handling. Proper storage is critical to maintain stability. The peptide should be kept in a tightly sealed container, protected from light and moisture, at temperatures between 2-8°C. Long-term storage at room temperature may lead to degradation, reducing efficacy. Manufacturers should conduct stability testing to determine shelf life under specific conditions.

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B2B Procurement Guide

When sourcing pentadecapeptide, B2B buyers should prioritize suppliers with proven expertise in peptide synthesis. Key procurement criteria include purity (≥95%), sequence verification, and batch-to-batch consistency. Request certificates of analysis (CoA) and third-party testing reports to ensure quality. Price varies based on purity, order volume, and supplier reputation. Bulk purchases may qualify for discounts, but buyers should balance cost with quality assurance. Reliable suppliers often provide technical support for formulation integration. Consider lead times and shipping conditions, as peptides may require cold chain logistics to preserve integrity.

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