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Pentaacetylgalactose

Updated: 2026-07-22

Overview

Pentaacetyl Galactose is a chemically modified form of galactose where all five hydroxyl groups are acetylated. It is commonly used as an intermediate in organic synthesis and carbohydrate chemistry. The compound is particularly valuable in the production of glycosides and other sugar derivatives. Due to its acetylated structure, Pentaacetyl Galactose is more stable and less reactive than its non-acetylated counterpart, making it suitable for various chemical transformations. It is widely utilized in pharmaceutical research for the development of glycoconjugates and other bioactive molecules.

Physical and Chemical Properties

β-D-半乳糖五乙酸酯 CAS100-53-8 选择性1-O-脱乙酰作用 国化化学山东国化化学有限公司

Pentaacetyl Galactose appears as a white crystalline powder with a molecular weight of 390.34 g/mol. It is soluble in common organic solvents such as chloroform, methanol, and dimethyl sulfoxide (DMSO), but has limited solubility in water. The compound is hygroscopic, meaning it can absorb moisture from the air, which may affect its stability over time. It has a melting point range of approximately 100-105°C. Proper storage conditions are essential to maintain its purity and prevent degradation.

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Main Applications

Pentaacetyl Galactose is primarily used in biochemical and pharmaceutical research. It serves as a key intermediate in the synthesis of complex carbohydrates and glycoconjugates, which are important in drug development and vaccine production. In addition, the compound is employed in carbohydrate chemistry to study glycosylation reactions and enzyme mechanisms. Its acetyl groups can be selectively removed or modified, allowing for the creation of tailored sugar derivatives for specific applications.

Safety and Storage

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Pentaacetyl Galactose should be handled with care to avoid inhalation or skin contact. Personal protective equipment (PPE), including gloves and safety goggles, is recommended when working with this chemical. Storage should be in a cool, dry place, away from light and moisture. Properly sealed containers are essential to prevent exposure to air, which could lead to hydrolysis or other degradation processes. Always refer to the material safety data sheet (MSDS) for detailed safety guidelines.

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B2B Procurement Guide

When procuring Pentaacetyl Galactose, it is crucial to verify the CAS number (4163-60-4) and purity specifications. Reputable suppliers should provide certificates of analysis (CoA) to ensure quality and consistency. Prices can vary significantly based on purity and quantity, typically ranging from $50 to $200 per gram. Bulk purchases may offer cost savings, but buyers should assess supplier reliability and lead times. Consider working with suppliers who specialize in fine chemicals and have a track record of quality assurance.

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