Overview
Bacillus subtilis is a versatile, Gram-positive bacterium renowned for its ability to form durable endospores, enabling survival in harsh conditions. It is non-pathogenic and widely studied for its applications in agriculture, biotechnology, and industry. The bacterium is a model organism for research due to its genetic tractability and rapid growth. First identified in the 19th century, B. subtilis is naturally found in soil and decomposing plant matter. Its resilience and metabolic flexibility make it valuable for producing enzymes, antibiotics, and bioactive compounds. In agriculture, it serves as a biocontrol agent, suppressing plant pathogens and promoting growth.
Physical and Chemical Properties
Bacillus subtilis is rod-shaped, typically 2–4 µm in length, and forms oval endospores under stress. It thrives in aerobic conditions but can survive anaerobically. The bacterium produces enzymes like amylases, proteases, and cellulases, which are vital for industrial processes. Its spores are highly resistant to heat, radiation, and chemicals, making them ideal for long-term storage and commercial formulations. In liquid cultures, B. subtilis exhibits turbid growth, while on solid media, it forms opaque, creamy colonies. The bacterium’s cell wall contains teichoic acids, contributing to its Gram-positive staining.
Main Applications
In agriculture, B. subtilis is used as a probiotic for livestock and a biocontrol agent to combat fungal and bacterial plant diseases. It enhances nutrient uptake and stimulates plant immune responses. Industrial applications include enzyme production (e.g., detergents, textiles) and fermentation for antibiotics like bacitracin. The pharmaceutical industry leverages B. subtilis for recombinant protein production and vaccine development. In environmental biotechnology, it aids in wastewater treatment and bioremediation due to its ability to degrade complex organic compounds. Consumer products like probiotic supplements also utilize its beneficial properties.
Safety and Storage
Bacillus subtilis is classified as Generally Recognized as Safe (GRAS) by regulatory agencies. However, handling requires standard microbiological practices to avoid contamination. Spores should be stored in airtight containers at 4°C or freeze-dried for long-term preservation. Avoid exposure to extreme pH or temperatures above 80°C, which may reduce viability. In industrial settings, ensure proper ventilation when handling powdered formulations. Disposal should follow local biosafety guidelines, though the bacterium poses minimal environmental risk.
B2B Procurement Guide
When sourcing B. subtilis, prioritize suppliers with certified strain libraries and quality control measures. Confirm the strain’s intended use (e.g., agriculture, industry) and viability specifications (CFU/g). Request certificates of analysis for purity and absence of contaminants. Bulk pricing varies by formulation (powder, liquid) and spore concentration. For large-scale orders, negotiate contracts with suppliers offering technical support and batch consistency. Consider regional availability to minimize shipping costs and storage delays.
Related Manufacturers
- 主营：研突破、转座酶、重组酶、大肠杆菌、连接酶、研试剂、(5×)(with、recombinant、结合蛋白、胶体染料、核酸染料、助力科研、泛素蛋白、实验室用品、重组肠激酶、电泳缓冲液、拓扑异构酶、热敏磷酸酶、检测试剂盒、全能核酸酶、核酸外切酶、核酸内切酶、连接试剂盒、碱性磷酸酶、微球菌核酸酶
- 主营：科研试剂、高效试剂
- 主营：抗体、感受态、培养基、试剂盒、层析柱、填料、生物试剂、化学试剂
- 主营：微生物菌种、标准菌株、益生菌、蔬菜芽胞杆菌、食用菌
- 主营：环戊酮、甲酸镍、阻燃剂、草酸镧、钼酸铵、催化剂、钒酸铋、溴氨酸、硝酸锆、碳酸镧、白僵菌、磷酸铁、钨酸酐、氟化镧、视黄醇、叔丁醇、杀螨剂、杀虫剂、醋酸钬、抗粘剂、氟化镥、肟菌酯、氢化钠、氯铂酸、氟化镁
- 主营：ELISA试剂盒、PCR试剂盒、科研试剂
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、幼虫芽胞杆菌检测、蛋白、抗体、细胞、检测试剂盒
- 主营：试剂盒、elisa试剂盒、细胞、pcr试剂盒
- 主营：igg抗体、糖蛋白、试剂盒、脂蛋白、人瘦素、粗纤维、猪睾酮、烯二酮、nad激酶、测试盒、牛瘦素、牛胆酸、原果胶、磷酸酶、犬肾素、含水量、人蛋白、甜菜碱、igm抗体、dna抗体、磷脂酶、大鼠超、犬叶酸、人胆酸、样受体
- 主营：检测方、钠尿肽、试剂盒、同源物、ep300检测、结合蛋白、大鼠c-肽(、微球蛋白、抗胰蛋白酶、淋巴瘤因子、蛋白磷酸酶、死亡激动剂、核心域蛋白1、大鼠e选择素、大鼠janus激酶、激活蛋白激酶、大鼠ⅱ型胶原、大鼠ⅳ型胶原、大鼠klotho蛋白、细胞激活因子、大鼠ⅲ型胶原、大鼠nadh脱氢酶1、大鼠ⅵ型胶原α1、elisa 检测试剂盒
- 主营：10ul吸头、巴氏吸管、离心管、透析袋、琼脂糖、国产试剂
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、蛋白、抗体、细胞
- 主营：培养基、培养皿、菌检测、蜡样芽胞杆菌培养基、菌落计数器、水质检测、ms培养基、微生物检测仪器设备、接种环、微生物检验、微生物检测、程控定量封口机、支原体培养基、路桥培养基、马铃薯葡萄糖琼脂培养基、三药培养基、海博培养基、菌种鉴定
- 主营：折射仪、钼酸铵、弹簧钢、分装瓶、指示剂、水分仪、方钢坯、合金钢、容器板、离子计、测定仪、容器钢、六角钢、测试片、样品瓶、浊度计、穿线管、齿轮钢、测试笔、切定尺、样品杯、清洗液、比色皿、排型钢、移液管
- 主营：霉菌消毒剂、车间消毒、食品厂消毒、拉秧芽孢杆菌灭菌、空气消毒、GMP车间消毒、杀孢子剂、洁净车间消毒、过氧化氢银离子、杀菌剂、冷库消毒、消毒液、消毒剂、除霉剂、除霉菌、防霉剂、霉菌真菌、霉菌孢子、消毒杀菌、管道消毒、去除生物膜、灭菌剂、杀灭芽孢、杀灭洋葱伯克