Overview
Pachymic Acid is a bioactive triterpenoid compound extracted from Poria cocos, a fungus widely used in traditional Chinese medicine. It has garnered significant attention for its diverse pharmacological activities, including anti-inflammatory, anti-tumor, and hepatoprotective effects. The compound is commonly utilized in both herbal formulations and modern pharmaceutical research. Pachymic Acid is particularly valued for its ability to modulate immune responses and inhibit the growth of certain cancer cells. Its molecular structure, characterized by a lanostane skeleton, contributes to its unique biological activities. Research continues to explore its potential in treating various diseases, making it a compound of interest in the medical and scientific communities.
Physical and Chemical Properties
Pachymic Acid appears as a white to off-white crystalline powder with a melting point around 250-252°C. It is soluble in organic solvents such as DMSO, methanol, and ethanol but exhibits poor solubility in water. This solubility profile is crucial for its extraction and formulation processes. The compound's stability is influenced by environmental factors, requiring storage in cool, dry conditions to prevent degradation. Its molecular weight of 496.77 g/mol and specific structural features, including hydroxyl and carboxylic acid groups, play a key role in its interactions with biological targets.
Main Applications
Pachymic Acid is primarily used in the pharmaceutical industry, where it is incorporated into drugs and supplements for its therapeutic properties. It is a key component in traditional Chinese medicine, often prescribed for its anti-inflammatory and immune-modulating effects. In modern medicine, research has highlighted its potential in cancer therapy, particularly in inhibiting tumor growth and metastasis. Additionally, its hepatoprotective properties make it valuable in treating liver disorders. The compound is also explored for its neuroprotective effects, suggesting broader applications in neurodegenerative diseases.
Safety and Storage
While Pachymic Acid is generally considered safe for medicinal use, proper handling is essential to avoid adverse effects. Direct contact with skin or eyes should be avoided, and protective equipment such as gloves and goggles is recommended during handling. Storage conditions are critical to maintaining the compound's stability. It should be kept in a tightly sealed container, away from light and moisture, at room temperature or below. Prolonged exposure to unfavorable conditions can lead to degradation, reducing its efficacy.
B2B Procurement Guide
When procuring Pachymic Acid, buyers should prioritize suppliers who provide certificates of analysis (CoA) to verify purity and composition. The reference price ranges between $50 and $200 per gram, depending on purity levels and supplier reputation. It is advisable to source the compound from reputable manufacturers with a track record of compliance with Good Manufacturing Practices (GMP). Buyers should also ensure that the product meets regulatory requirements in their respective regions, particularly for pharmaceutical and dietary supplement applications.
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