Overview
Methyl 4-Nitrobenzoate is an organic ester derived from 4-nitrobenzoic acid. It is widely utilized in the pharmaceutical and chemical industries due to its role as a versatile intermediate. The compound is known for its stability and reactivity, making it valuable in synthetic chemistry. Its crystalline form and solubility in organic solvents facilitate easy handling in laboratory and industrial settings. The compound's nitro group enhances its reactivity, enabling its use in various chemical transformations.
Physical and Chemical Properties
Methyl 4-Nitrobenzoate appears as a white to light yellow crystalline powder with a molecular weight of 181.15 g/mol. It has a density of 1.28 g/cm³ and a melting point range of 94-96 °C. The compound is soluble in common organic solvents like ethanol and acetone but has limited solubility in water. Its stability under normal conditions makes it suitable for storage and transport, though it should be protected from extreme heat and light to prevent decomposition. The nitro group contributes to its electrophilic character, making it reactive in nucleophilic substitution reactions.
Main Applications
Methyl 4-Nitrobenzoate is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. Its reactivity allows it to participate in various chemical reactions, including esterifications and nitrations. In the pharmaceutical industry, it serves as a building block for active pharmaceutical ingredients (APIs). In dye manufacturing, it contributes to the production of vibrant and stable colorants. Its versatility also extends to agrochemicals and specialty chemicals.
Safety and Storage
Handling Methyl 4-Nitrobenzoate requires caution to avoid inhalation, ingestion, or skin contact. Personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be stored in a cool, dry place away from direct sunlight and moisture to maintain its stability. In case of exposure, immediate measures such as rinsing with water or seeking medical attention may be necessary. Proper ventilation is recommended when working with the compound to minimize inhalation risks.
B2B Procurement Guide
When procuring Methyl 4-Nitrobenzoate, buyers should prioritize suppliers with a proven track record of quality and compliance. Key considerations include verifying the CAS number (619-50-1) and ensuring the product meets the required purity specifications. Prices typically range from $50 to $100 per kilogram, depending on purity and order volume. Bulk purchases may offer cost savings. It's advisable to request samples and certificates of analysis (CoA) before finalizing large orders to ensure consistency and quality.
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