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p-Methoxybenzene

Updated: 2026-07-22

Overview

p-Methoxytoluene, chemically known as 4-methylanisole, is an organic compound widely used as an intermediate in various industries. It is a colorless to pale yellow liquid with a characteristic aromatic odor. The compound is synthesized through the methylation of phenol or other related processes. p-Methoxytoluene is valued for its role in the production of fragrances, pharmaceuticals, and agrochemicals. Its chemical stability and reactivity make it a versatile building block in organic synthesis. The compound is commercially available in different purity grades to meet specific industrial needs.

Physical and Chemical Properties

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p-Methoxytoluene exhibits a boiling point of 176-177°C and a melting point of -23°C, making it a liquid at room temperature. Its density is approximately 0.969 g/cm³, and it is slightly soluble in water but highly soluble in common organic solvents like ethanol and ether. The compound is flammable and should be handled with care to avoid ignition sources. It is relatively stable under normal conditions but can decompose under extreme heat, releasing carbon monoxide and other hazardous gases. Its aromatic structure contributes to its use in fragrance formulations.

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Main Applications

The primary use of p-Methoxytoluene is as an intermediate in the fragrance industry, where it contributes to the synthesis of musk and floral scents. It is also employed in pharmaceutical manufacturing, particularly in the production of antihistamines and other active ingredients. In agrochemicals, p-Methoxytoluene serves as a precursor for pesticides and herbicides. Its chemical properties allow for modifications that enhance the efficacy of these products. Additionally, it finds niche applications in research and specialty chemical synthesis.

Safety and Storage

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p-Methoxytoluene is classified as an irritant, posing risks to skin and eyes upon contact. Proper personal protective equipment (PPE), including gloves and goggles, is recommended during handling. Inhalation of vapors should be avoided, and work areas must be well-ventilated. Storage should be in tightly sealed containers, away from heat sources and open flames. The compound is sensitive to light and moisture, so it is best kept in dark, dry conditions. Spills should be contained and cleaned up immediately using appropriate absorbents.

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B2B Procurement Guide

When procuring p-Methoxytoluene, buyers should prioritize suppliers with verified certifications, such as ISO or GMP, to ensure quality and consistency. Purity specifications (e.g., 98% or higher) should be clearly stated in purchase agreements. Bulk purchases often come with cost advantages, but storage capabilities must be assessed to maintain product integrity. Shipping conditions, such as temperature control and hazardous material labeling, are critical for safe transportation. Buyers are advised to request samples and conduct lab tests before large-scale orders.

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