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p-Methoxyacetanilide

Updated: 2026-07-15

Overview

p-Methoxyacetanilide is an organic compound widely used as an intermediate in the pharmaceutical and dye industries. It is synthesized through the acetylation of p-anisidine and is known for its stability and versatility in chemical reactions. This compound is particularly valued in the production of analgesics and antipyretics, as well as in the synthesis of various dyes. Its consistent quality and reliable performance make it a preferred choice for industrial applications.

Physical and Chemical Properties

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p-Methoxyacetanilide appears as a white crystalline powder with a melting point of 130-132°C. It is soluble in organic solvents like ethanol and ether but has limited solubility in water. The compound is stable under normal conditions and does not pose significant flammability risks. Its molecular structure includes a methoxy group attached to a phenyl ring, which influences its reactivity and solubility characteristics.

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Main Applications

The primary use of p-Methoxyacetanilide is as an intermediate in the synthesis of pharmaceuticals, particularly in the production of pain relievers and fever reducers. It is also employed in the dye industry to create various colorants. Additionally, this compound serves as a building block in organic synthesis, facilitating the creation of more complex molecules for research and industrial purposes.

Safety and Storage

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p-Methoxyacetanilide should be handled with care to avoid inhalation, ingestion, or skin contact. Proper protective equipment, such as gloves and goggles, is recommended during use. Storage conditions should include a cool, dry environment away from direct sunlight and moisture. Proper labeling and segregation from incompatible substances are essential to maintain safety and product integrity.

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B2B Procurement Guide

When procuring p-Methoxyacetanilide, buyers should verify the CAS number (51-66-1) and ensure the product meets required purity standards. Reputable suppliers should provide certificates of analysis and comply with industry regulations. Bulk purchases may offer cost advantages, but buyers should also consider storage capabilities and shelf life. Establishing long-term relationships with reliable suppliers can ensure consistent quality and timely delivery.

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