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p-Ethoxy

Updated: 2026-07-18

Overview

Phenetole, also known as ethyl phenyl ether or ethoxybenzene, is an organic compound belonging to the class of aromatic ethers. It is a colorless liquid with a pleasant, aromatic odor, making it useful in various industrial applications. Phenetole is primarily used as a solvent and as an intermediate in the synthesis of other organic compounds. Its chemical stability and volatility make it a versatile component in laboratories and industrial settings. Phenetole is synthesized through the Williamson ether synthesis, which involves the reaction of phenol with ethyl halides in the presence of a base. This method is widely employed due to its efficiency and the high purity of the resulting product. The compound's unique properties, such as its solubility in organic solvents and insolubility in water, further enhance its utility in chemical processes.

Physical and Chemical Properties

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Phenetole exhibits several notable physical and chemical properties. It is a colorless liquid with a density of 0.967 g/cm³ and a boiling point of 170 °C. Its melting point is -30 °C, and it is highly soluble in organic solvents like alcohol and ether but insoluble in water. The compound is volatile and flammable, requiring careful handling and storage. Chemically, phenetole is stable under normal conditions but can undergo reactions typical of ethers, such as cleavage under acidic conditions. Its aromatic ring allows for electrophilic substitution reactions, making it a valuable intermediate in organic synthesis. Phenetole's low reactivity with water and its ability to dissolve a wide range of organic compounds contribute to its widespread use in laboratories and industrial applications.

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Main Applications

Phenetole serves as a key solvent in various chemical processes due to its ability to dissolve numerous organic compounds. It is particularly useful in the pharmaceutical and perfumery industries, where it acts as an intermediate in the synthesis of more complex molecules. Its pleasant aroma also makes it a component in some fragrances. In addition to its role as a solvent, phenetole is employed in the production of dyes, resins, and other specialty chemicals. Its stability and reactivity make it a preferred choice for organic synthesis, especially in reactions requiring an ether functional group. The compound's versatility ensures its continued relevance in both research and industrial settings.

Safety and Storage

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Phenetole is a flammable liquid and should be handled with care to avoid fire hazards. It should be stored in a cool, dry, well-ventilated area away from heat sources and open flames. Proper grounding of containers is essential to prevent static electricity buildup, which could ignite the vapor. Exposure to phenetole may cause irritation to the skin, eyes, and respiratory tract. Personal protective equipment (PPE), such as gloves and goggles, should be worn when handling the compound. In case of spills, absorb the liquid with an inert material and dispose of it according to local regulations. Proper ventilation is crucial to minimize inhalation risks.

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B2B Procurement Guide

When procuring phenetole, it is essential to verify the supplier's credentials and ensure they provide comprehensive safety data sheets (SDS). The purity of the compound should meet industry standards, typically 98% or higher for most applications. Buyers should also consider the packaging options, such as drums or smaller containers, based on their usage requirements. Price negotiations should take into account the current market trends, with phenetole commonly priced between $50 and $100 per kg. Bulk purchases may offer cost savings, but storage capacity and shelf life should be considered. Establishing a reliable supply chain is crucial to avoid disruptions in production processes.

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