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Oxyquinoline

Updated: 2026-07-15

Overview

Oxyquinoline, also known as 8-hydroxyquinoline, is an organic compound with a wide range of industrial and pharmaceutical applications. It is a chelating agent and exhibits antimicrobial properties, making it valuable in various fields. The compound is synthesized through the Skraup reaction or other quinoline derivatization methods. Oxyquinoline is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. Its ability to form stable complexes with metal ions also makes it useful in analytical chemistry and metallurgy. The compound is available in various purity grades, typically ranging from 98% to 99.9% for industrial use.

Physical and Chemical Properties

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Oxyquinoline is a white to yellowish crystalline powder with a characteristic odor. It has a melting point of 76-79 °C and a boiling point of 267 °C. The compound is soluble in organic solvents like ethanol and acetone but only slightly soluble in water. One of the key chemical properties of oxyquinoline is its ability to act as a chelating agent, forming stable complexes with metal ions such as copper, iron, and aluminum. This property is exploited in various industrial processes, including metal extraction and corrosion inhibition. The compound also exhibits fluorescence, which is utilized in analytical applications.

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Main Applications

Oxyquinoline is widely used in the pharmaceutical industry as an intermediate for the synthesis of antiseptics, antifungals, and other medicinal compounds. Its antimicrobial properties make it effective in topical treatments and preservatives. In agriculture, oxyquinoline is used as a fungicide and bactericide. It is also employed in the production of agrochemicals to protect crops from fungal infections. Additionally, the compound's chelating properties are utilized in analytical chemistry for metal ion detection and in metallurgy for metal extraction and purification.

Safety and Storage

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Oxyquinoline is classified as an irritant and should be handled with care. Proper personal protective equipment (PPE), including gloves and goggles, is recommended to prevent skin and eye contact. The compound should be stored in a cool, dry place away from light and moisture to maintain its stability. In case of accidental exposure, affected areas should be rinsed immediately with plenty of water. Proper ventilation is essential when handling oxyquinoline to avoid inhalation of dust or vapors. Disposal should comply with local environmental regulations to prevent contamination.

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B2B Procurement Guide

When procuring oxyquinoline, it is crucial to verify the purity and quality of the product. Suppliers should provide a Certificate of Analysis (COA) detailing the compound's purity, moisture content, and other relevant parameters. Bulk buyers should consider the form (powder or solution) and purity grade required for their specific application. Prices vary depending on quantity and purity, with higher purity grades commanding premium prices. It is advisable to source from reputable manufacturers with a track record of consistent quality and reliable supply.

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