Overview
Olodaterol is a selective long-acting beta2-adrenergic agonist (LABA) primarily used in the management of chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles in the airways, thereby improving breathing. Olodaterol is commonly administered via inhalation and is known for its prolonged duration of action, which provides relief for up to 24 hours. It is often prescribed as part of a combination therapy for better disease management. Developed by Boehringer Ingelheim, olodaterol has been approved by regulatory authorities such as the FDA and EMA for clinical use. Its efficacy and safety profile make it a preferred choice among healthcare providers for COPD patients requiring long-term bronchodilation.
Physical and Chemical Properties
Olodaterol is a white to off-white powder with a molecular weight of 368.43 g/mol. It is soluble in water and various organic solvents, which facilitates its formulation into inhalable solutions. The compound's chemical stability under standard storage conditions ensures its longevity and efficacy. The molecular formula of olodaterol is C21H24N2O4, reflecting its complex structure designed for selective beta2-adrenergic receptor activation. Its solubility and stability are critical for its pharmaceutical applications, ensuring consistent performance in clinical settings.
Main Applications
Olodaterol is primarily used in the treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It is often prescribed as a maintenance medication to prevent bronchospasms and improve airflow in patients with persistent respiratory symptoms. In addition to standalone use, olodaterol is frequently combined with other medications such as tiotropium (an anticholinergic) to enhance therapeutic outcomes. Its long-acting nature reduces the frequency of dosing, improving patient adherence and quality of life.
Safety and Storage
Olodaterol should be stored in a cool, dry place, protected from light and moisture to maintain its stability. Proper handling is essential to avoid inhalation or direct contact, which could lead to adverse effects. Always use personal protective equipment (PPE) when working with the compound in a laboratory or industrial setting. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines. In case of accidental exposure, seek medical attention immediately. Proper storage and handling ensure the compound's efficacy and safety throughout its shelf life.
B2B Procurement Guide
When procuring olodaterol, B2B buyers should prioritize suppliers who comply with pharmaceutical standards such as GMP (Good Manufacturing Practice). Verification of the CAS number (868049-49-4) and purity levels is essential to ensure product authenticity and quality. Price ranges for pharmaceutical-grade olodaterol typically fall between $50 and $100 per gram, depending on quantity and supplier. Bulk purchases may offer cost advantages. Always request certificates of analysis (CoA) and ensure proper documentation for regulatory compliance.