Overview
Oleanolic Acid Acetate is a semisynthetic derivative of oleanolic acid, a naturally occurring triterpenoid found in plants like olive and clove. It is valued for its enhanced bioavailability and pharmacological properties compared to its parent compound. The acetate modification improves its solubility in organic formulations, making it suitable for drug development and cosmetic applications. In industrial contexts, it is synthesized under controlled conditions to ensure high purity and consistency. Its role as an intermediate in steroid-like drug synthesis and its bioactive potential have driven demand in B2B markets, particularly from pharmaceutical and nutraceutical manufacturers.
Physical and Chemical Properties
Oleanolic Acid Acetate is characterized by its crystalline solid form and stability under recommended storage conditions. Its molecular structure includes a carboxyl group and an acetylated hydroxyl group, which contribute to its reactivity and solubility profile. The compound exhibits low water solubility but dissolves readily in polar organic solvents, a feature critical for formulation processes. Thermal analysis shows a sharp melting point around 280°C, indicative of its purity. Spectroscopic methods (e.g., NMR, IR) are commonly used for quality verification. Its stability in acidic and neutral conditions makes it suitable for oral drug formulations, though it may degrade under prolonged exposure to UV light or high humidity.
Main Applications
In pharmaceuticals, Oleanolic Acid Acetate is investigated for its anti-inflammatory, anticancer, and liver-protective effects. It serves as a key intermediate in synthesizing derivatives with improved therapeutic indices. Preclinical studies highlight its potential in treating metabolic disorders and skin conditions. The cosmetic industry utilizes it as an active ingredient in anti-aging and skin-repair products due to its antioxidant properties. Research laboratories employ it as a reference standard or biochemical probe. Its dual role in therapeutics and cosmetics underscores its versatility in B2B supply chains, with demand segmented by purity grades (e.g., >95% for research, >98% for pharmaceuticals).
Safety and Storage
While Oleanolic Acid Acetate is not classified as highly hazardous, standard laboratory precautions are advised. Use personal protective equipment (PPE) to prevent skin contact or inhalation of dust. Spills should be contained with inert absorbents and disposed of as chemical waste. Long-term storage requires protection from moisture and oxidation. Sealed containers with desiccants are recommended, ideally under refrigeration (2-8°C). Bulk quantities should be stored in climate-controlled warehouses with compliance to local chemical storage regulations. Stability studies suggest a shelf life of 2-3 years when stored properly.
B2B Procurement Guide
When sourcing Oleanolic Acid Acetate, prioritize suppliers with documented quality control processes (e.g., ISO-certified manufacturers). Request certificates of analysis (CoA) detailing purity (HPLC/GC), residual solvents, and heavy metal content. Batch-to-batch consistency is critical for pharmaceutical applications. Pricing varies based on quantity (bulk discounts apply) and purity. Negotiate contracts with clauses for sample testing and lead-time guarantees. For international procurement, consider logistics costs and regulatory compliance (e.g., REACH, FDA). Establish partnerships with suppliers offering technical support and customized synthesis services for derivative development.
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