Overview
o-Toluidine is an organic compound belonging to the toluidine family, specifically the ortho-isomer of methylaniline. It is a versatile intermediate in chemical synthesis, particularly valued in the production of dyes and agrochemicals. The industrial-grade variant is commonly used in B2B applications where high purity is not strictly necessary, making it a cost-effective choice for large-scale manufacturing processes. Its production typically involves the nitration of toluene followed by reduction.
Physical and Chemical Properties
As a liquid at room temperature, o-toluidine exhibits characteristic aromatic amine properties. It is weakly basic and can form salts with acids. The compound is flammable, with a flash point of 85°C, and has a distinct amine odor. Chemically, the methyl group ortho to the amino group influences its reactivity, making it less basic than aniline but more reactive in electrophilic aromatic substitution reactions. This property is exploited in dye chemistry where it serves as a coupling component.
Main Applications
The primary use of industrial-grade o-toluidine is in the manufacture of dyes, particularly azo dyes which account for approximately 60% of its consumption. It's also a key intermediate for rubber chemicals like vulcanization accelerators. In agrochemical production, it serves as a building block for certain herbicides and fungicides. Emerging applications include its use in pharmaceutical intermediates, though this typically requires higher purity grades than industrial quality.
Safety and Storage
o-Toluidine requires careful handling due to its toxicity and potential carcinogenicity. Proper PPE including gloves, goggles and respiratory protection should be used when handling. The substance is classified as a Category 2 carcinogen under EU regulations. Storage should be in tightly sealed containers away from oxidizing agents. Secondary containment is recommended to prevent environmental contamination in case of leaks. The compound is stable under normal conditions but may decompose at high temperatures.
B2B Procurement Guide
When sourcing industrial-grade o-toluidine, buyers should prioritize suppliers with proper chemical handling certifications. Typical packaging includes 200kg steel drums or 1000kg IBCs, with pricing often volume-dependent. Quality verification should include checking for water content (should be <0.5%) and purity (typically 98-99%). Long-term contracts are common in this market due to price volatility. Transportation requires hazardous chemical labeling and documentation.
Related Manufacturers
- 主营：多聚甲醛、正硅酸乙酯28 40、正十二烷、邻甲苯胺、二甲苯、四氢呋喃、液体丁腈橡胶、乙二醛、四氯乙烯、三氯乙烯、环己酮、环己胺、二甲基甲酰胺、二甲基乙酰胺、航空煤油、石油醚、糠醛、亚氯酸钠、铬酸酐、顺酐、保险粉、无水乙醇、异丙醇、二氯甲烷、醋酸乙酯、醋酸甲酯
- 主营：增塑洗涤剂、间二甲苯、乳化剂、邻甲苯胺、防冻液、丙二醇、三甲苯、苯乙烯、溶剂油、钛酸四丁酯、甲醇、乙醇、仲辛醇、异丙醇、85磷酸、碳酸丙烯酯、甲基丙烯酸、丙烯酸羟乙酯、二甲苯、脂肪酸甲酯、甲酸、氨水、丙烯酸、草酸、聚乙二醇
- 主营：戊二醇、聚醚胺、苯乙烯、邻甲苯胺、苯乙酮、正戊烷、正辛烷、异己烷、三乙胺、叔丁醇、二甲苯、环戊烷、甲酰胺、仲丁醇、异辛酸、二乙胺、异丁醇、氯化苄、异壬酸、异辛烷、丙二醇、正辛醇、乙二醇、二氯甲烷、二氯乙烷、氯化石蜡
- 主营：多聚甲醛、环己胺、正硅酸乙酯28 40、邻甲苯胺、正十二烷、异丙醇、无水乙醇、铬酸酐、亚氯酸钠、二甲基甲酰胺、硫酸羟胺、戊二酸二甲酯、邻苯二甲酸二乙酯、二甲苯、二氯甲烷、环己烷、四氯乙烯、环己酮、环氧氯丙烷、甲醇、甲酸、乙腈、苯酚、乙二醇乙醚醋酸酯、醋酸丁酯
- 主营：四氢噻吩、乙硫醇、单氰胺、邻甲苯胺样品实验、二甲基二硫醚、3-甲硫基丙醛、四氢吡咯、邻氯苯腈、噻吩、盐酸羟胺、硬脂酸锌、异丙胺、氯乙酸、氟硼酸
- 主营：工业级氟硼酸、四氢噻吩、农药中间体
- 主营：碳酸二甲酯、二乙二醇丁醚、顺酐、硝酸铁、一乙醇胺、邻苯二甲酸二辛酯、乙酸乙酯、溶剂油、四氢呋喃、二甲基乙酰胺、乙二醇二醋酸酯、一正丁胺
- 主营：食品酒精、无水乙醇、白凡士林、工业级白油、食品级白油、三乙醇胺、溶剂油、P507萃取剂、二甲基丙烯酰胺、正十二烷、8-羟基喹啉、阻聚剂701、聚乙二醇、三乙二醇、桐油、1227杀菌剂、乙醇钠、乙酸乙酯、二甲苯
- 主营：保险粉、苯乙烯、二甲苯、邻甲苯胺厂家、正庚烷、丙三醇、氯化钙、环己烷、冰醋酸、醋酸钠、环己酮、正己烷、二氯甲烷、环己胺、石油醚、乙醇、碳酸丙烯酯、苯甲醇、三乙醇胺、航空煤油、多聚甲醛、乙腈、吗啉、二甲胺、乙二醇丁醚
- 主营：十六烷基三甲基溴化铵、十二烷基甜菜咸、乳化剂、邻甲苯胺、亚磷酸三丁酯、棕榈油、钛酸四丁酯、钛酸四乙酯
- 主营：甲基硅酸、麦芽糖浆、环氧大豆油、邻甲苯胺、甲酸钙、甘油、磺酸、乳化剂、食品添加剂、玉米淀粉、航煤、腐植酸钠、二甘醇、妥尔油、全水溶肥料、糖果饮料制作、二甲基硅油、消泡剂、三乙醇胺、次氯酸钠、二价酸酯、丙三醇、丙二醇、醋酸丁酯
- 主营：化工
- 主营：脱模剂、碘酸钾、磷酸镁、维生素c、维生素b1、维生素b6、维生素d3、二硫化钼、吡啶硫铜、香草香精、芥酸酰胺、乙基纤维素、次氯酸钙、九水硫化钠、EVA乳液、水玻璃、硅酸钠
- 主营：有机化工原料、甲醇、二氯甲烷、环己酮、环己烷、苯乙烯、吗啉、氯化苯、丙烯酸异辛酯、二甲基乙酰胺、醋酸乙酯、丙烯酸丁酯、亚硝酸钠、叔丁醇、环己胺、异佛尔酮、邻二甲苯、醋酸正丙酯、甲酸乙酯、甲酰胺、丙烯酸、二丙二醇
- 主营：甲基磺酸、乙醇钠、盐酸胍、邻甲苯胺、对氯苯甲酸、丙酸乙酯、乙二醛、正丁醚、十二烷基苯、对二氯苯、硫醇、多聚磷酸、戊二醛、二氯甲烷、碳酸钾、双氰胺、偶氮二异丁腈、正己醇、乙腈、二氧六环、水杨醛、对甲酚、吗啉、咪唑、四甲基乙二胺