Overview
2-Methoxyacetophenone, commonly referred to as o-Methoxyacetophenone, is an organic compound with a distinctive aromatic odor. It is primarily used as an intermediate in the synthesis of pharmaceuticals, fragrances, and other fine chemicals. The compound is characterized by its molecular formula C9H10O2 and a molecular weight of 150.17 g/mol. Its CAS number, 579-74-8, is a unique identifier for chemical registration and safety data. In industrial settings, 2-Methoxyacetophenone is valued for its role in producing more complex molecules. Its applications span across various sectors, including the pharmaceutical industry, where it serves as a building block for active pharmaceutical ingredients (APIs). The compound's aromatic properties also make it a popular choice in the fragrance industry.
Physical and Chemical Properties
2-Methoxyacetophenone is a colorless to pale yellow liquid with a density of 1.09 g/cm³. It has a boiling point range of 245-247 °C, making it relatively stable under standard conditions. The compound is soluble in common organic solvents such as ethanol and ether but has limited solubility in water. One of the key chemical properties of 2-Methoxyacetophenone is its reactivity as a ketone. It can undergo various chemical reactions, including reduction to form alcohols or condensation reactions to create more complex structures. These properties make it a versatile intermediate in organic synthesis.
Main Applications
The primary use of 2-Methoxyacetophenone is in the pharmaceutical industry, where it acts as an intermediate in the synthesis of APIs. Its aromatic structure allows it to be incorporated into more complex molecules that exhibit therapeutic effects. Additionally, the compound is used in the fragrance industry to create floral and herbal scents. Another significant application is in organic synthesis, where 2-Methoxyacetophenone serves as a precursor for various chemical reactions. Its ability to participate in multiple reaction pathways makes it a valuable tool for chemists working on drug discovery and material science.
Safety and Storage
2-Methoxyacetophenone should be handled with care to avoid inhalation or skin contact, which can cause irritation. Proper protective equipment, such as gloves and goggles, should be worn when working with this chemical. It is also advisable to work in a well-ventilated area to minimize exposure. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry place away from direct sunlight and oxidizing agents. Containers should be tightly sealed to prevent contamination and evaporation. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety guidelines.
B2B Procurement Guide
When procuring 2-Methoxyacetophenone, it is essential to verify the CAS number (579-74-8) to ensure you are purchasing the correct compound. Purity levels can vary between suppliers, so requesting a certificate of analysis (CoA) is recommended. Prices typically range from $50 to $100 per kg, depending on purity and supplier. It is also advisable to establish a relationship with a reliable supplier who can provide consistent quality and timely deliveries. For bulk purchases, negotiate terms that include safety data sheets and compliance with regulatory requirements. Always ensure that the supplier adheres to industry standards for chemical handling and transportation.
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