Overview
o-Hydroxycinnamic Acid, chemically known as 2-hydroxycinnamic acid, is an organic compound belonging to the class of hydroxycinnamic acids. It is structurally derived from cinnamic acid by the introduction of a hydroxyl group at the ortho position of the benzene ring. This modification imparts unique chemical and physical properties, making it valuable in various industrial applications. The compound is primarily synthesized through chemical reactions involving cinnamic acid derivatives or via biosynthesis pathways in certain plants. Its aromatic nature and functional groups contribute to its reactivity, particularly in organic synthesis and pharmaceutical manufacturing.
Physical and Chemical Properties
o-Hydroxycinnamic Acid appears as a white to pale yellow crystalline powder under standard conditions. It has a molecular weight of 164.16 g/mol and a melting point ranging between 210-215°C. The compound is soluble in common organic solvents such as ethanol, methanol, and ethyl acetate but exhibits limited solubility in water. Key chemical properties include its ability to absorb UV light, making it useful in UV-protective applications. The presence of both a carboxylic acid and a hydroxyl group allows for diverse chemical reactions, including esterification and condensation. Its stability under normal storage conditions makes it suitable for long-term use in industrial settings.
Main Applications
o-Hydroxycinnamic Acid is widely utilized as an intermediate in the pharmaceutical industry, particularly in the synthesis of active pharmaceutical ingredients (APIs). Its structural features make it a valuable precursor for drugs targeting inflammation and microbial infections. In the fragrance industry, it serves as a building block for synthesizing aromatic compounds with floral or spicy notes. Additionally, it is employed in organic synthesis for producing specialty chemicals, including UV stabilizers and polymer additives. Its versatility and reactivity make it a sought-after compound in research and industrial applications.
Safety and Storage
Handling o-Hydroxycinnamic Acid requires adherence to standard safety protocols to minimize exposure. It is advisable to use personal protective equipment (PPE), including gloves and safety goggles, to prevent skin and eye contact. Inhalation of dust or vapors should be avoided by working in a well-ventilated area or under a fume hood. For storage, the compound should be kept in a tightly sealed container in a cool, dry place, away from direct sunlight and moisture. Proper labeling and segregation from incompatible substances, such as strong oxidizers, are essential to ensure safety and stability during storage.
B2B Procurement Guide
When procuring o-Hydroxycinnamic Acid, B2B buyers should prioritize suppliers with a proven track record of quality and reliability. Key considerations include verifying the CAS number (614-60-8) and requesting a Certificate of Analysis (COA) to confirm purity and composition. Price negotiations should account for factors such as batch size, purity grade, and delivery terms. Bulk purchases often attract discounts, but buyers should balance cost with quality assurance. Establishing long-term partnerships with reputable suppliers can ensure consistent quality and timely delivery, minimizing disruptions in production processes.
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