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o-Hydroxybenzoate

Updated: 2026-07-20

Overview

Methyl salicylate, commonly known as wintergreen oil, is an organic ester derived from salicylic acid. It occurs naturally in plants such as wintergreen (Gaultheria procumbens) and sweet birch (Betula lenta). The compound is synthesized industrially for its medicinal and aromatic properties. Its characteristic minty aroma and analgesic effects make it a popular ingredient in topical pain relievers, flavorings, and fragrances. It is also used in small quantities as a food additive for its distinctive wintergreen flavor.

Physical and Chemical Properties

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Methyl salicylate is a colorless to pale yellow liquid with a strong, sweet, wintergreen-like odor. It has a molecular weight of 152.15 g/mol and a density of 1.174 g/cm³. The compound has a melting point of -8°C and a boiling point of 222°C. It is sparingly soluble in water but readily dissolves in organic solvents such as ethanol and ether. Methyl salicylate is stable under normal conditions but should be protected from prolonged exposure to heat and light to prevent degradation.

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Main Applications

Methyl salicylate is widely used in the pharmaceutical industry as an active ingredient in topical analgesics and anti-inflammatory creams. It provides temporary relief from muscle and joint pain due to its counterirritant properties. In the cosmetics industry, it is used in perfumes, soaps, and lotions for its pleasant fragrance. The food industry employs it as a flavoring agent in candies, chewing gums, and oral care products. Additionally, it serves as a denaturant in ethanol and as a pesticide in some agricultural applications.

Safety and Storage

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Methyl salicylate should be handled with care to avoid skin and eye irritation. Prolonged or repeated exposure may cause allergic reactions in sensitive individuals. Ingestion of large amounts can be toxic, leading to salicylate poisoning. Proper storage involves keeping the compound in a tightly sealed container in a cool, dry, and well-ventilated area away from heat sources and open flames. It is advisable to use personal protective equipment (PPE) such as gloves and goggles when handling the chemical.

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B2B Procurement Guide

When procuring methyl salicylate for B2B purposes, buyers should prioritize suppliers with certifications such as ISO, GMP, or FDA approvals, especially for pharmaceutical or food-grade applications. Verify the CAS number (119-36-8) and request certificates of analysis (CoA) to ensure product purity and quality. Prices typically range from $10 to $50 per kilogram, depending on purity and quantity. Bulk purchases may offer cost advantages. Ensure the supplier provides proper labeling, safety data sheets (SDS), and compliance with regional regulations.

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