o-Ethylaniline

Updated: 2026-09-16

Overview

o-Ethylaniline is an aromatic amine derivative of aniline, where an ethyl group is substituted at the ortho position of the benzene ring. It is primarily utilized as a chemical intermediate in industrial applications. The compound is notable for its role in the synthesis of dyes, pharmaceuticals, and agrochemicals due to its reactive amino group and aromatic structure. Its production involves ethylation of aniline under controlled conditions, often yielding a mixture of ortho and para isomers. o-Ethylaniline is distinguished by its specific reactivity patterns, making it valuable for targeted chemical synthesis.

Physical and Chemical Properties

o-Ethylaniline is a colorless to pale yellow liquid with a characteristic amine odor. It has a density of 0.983 g/cm³ and a boiling point range of 210-212°C. The compound is soluble in most organic solvents, such as ethanol and ether, but exhibits limited solubility in water. Chemically, it behaves as a typical aromatic amine, capable of undergoing reactions like diazotization, acylation, and alkylation. Its volatility and moderate toxicity necessitate careful handling to avoid inhalation or skin contact, which can lead to health hazards.

Main Applications

The primary use of o-Ethylaniline is as a building block in the synthesis of dyes, particularly azo dyes, which are widely used in textiles and inks. Its reactivity allows for the introduction of ethyl groups into complex molecular structures, enhancing colorfastness and solubility. In the pharmaceutical industry, it serves as an intermediate for drugs targeting cardiovascular and central nervous system conditions. Additionally, agrochemical manufacturers employ it in producing pesticides and herbicides, leveraging its ability to modify biological activity.

Safety and Storage

o-Ethylaniline requires stringent safety measures due to its toxic nature. It can cause skin irritation, respiratory distress, and systemic effects if improperly handled. Workers must use gloves, goggles, and respirators when handling the compound. Storage should be in tightly sealed containers placed in cool, well-ventilated areas, away from oxidizing agents and heat sources. Spills should be contained using inert absorbents and disposed of as hazardous waste, following local regulations.

B2B Procurement Guide

When procuring o-Ethylaniline, buyers should prioritize suppliers with certifications like ISO 9001 to ensure quality and consistency. Specifications such as purity (typically ≥98%) and moisture content should be clearly defined in purchase agreements. Bulk purchases often reduce costs, but storage capacity and shelf-life considerations must be evaluated. Logistics should account for hazardous material transport regulations, including proper labeling and documentation.