Overview
NS309 is a synthetic compound primarily used in scientific research to study potassium channels, specifically KCa2 and KCa3.1. It is known for its selective activation properties, making it valuable in cardiovascular and neurological research. Developed as a pharmacological tool, NS309 helps researchers understand the role of potassium channels in various physiological processes. Its ability to modulate these channels has potential therapeutic implications for conditions like hypertension and epilepsy.
Physical and Chemical Properties
NS309 appears as a white to off-white powder with a molecular weight of 352.86 g/mol. It is soluble in dimethyl sulfoxide (DMSO) and ethanol, which are commonly used solvents in laboratory settings. The compound's stability is maintained when stored at -20°C in a dry, dark environment. Its selective activation of KCa2 and KCa3.1 channels is its most notable chemical property, distinguishing it from other potassium channel modulators.
Main Applications
NS309 is predominantly used in academic and pharmaceutical research to investigate the function of potassium channels in cardiovascular and neurological systems. Its selective activation properties make it a valuable tool for studying diseases like hypertension, atrial fibrillation, and epilepsy. In addition to basic research, NS309 is explored for potential therapeutic applications. However, its use is currently limited to preclinical studies due to the need for further safety and efficacy evaluations.
Safety and Storage
When handling NS309, it is essential to use personal protective equipment, including gloves and safety goggles, to avoid skin and eye contact. The compound should be used in a well-ventilated area to minimize inhalation risks. Proper storage conditions are critical to maintaining NS309's stability. It should be kept at -20°C in a dry, dark place, away from moisture and light. Always check the material safety data sheet (MSDS) for updated safety guidelines.
B2B Procurement Guide
When procuring NS309 for research purposes, ensure that the supplier provides detailed purity certificates, typically above 98%. Proper documentation, including CAS number and molecular weight, should accompany the product. Given its specialized use, NS309 is often available in small quantities, such as 10mg vials, with prices ranging approximately $200-$500. Buyers should verify storage and shipping conditions to prevent degradation during transit.
Related Manufacturers
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