Norsynephrine

Updated: 2026-09-11

Overview

Norsynephrine, commonly known as octopamine, is an organic compound that functions as a sympathomimetic amine. It is structurally related to norepinephrine and is found naturally in some plants and animals. Norsynephrine is used in pharmaceutical research, dietary supplements, and as a precursor in chemical synthesis. Due to its role in the sympathetic nervous system, it has been studied for its potential effects on metabolism and energy expenditure. It is also used in some weight loss and performance-enhancing supplements, though its efficacy and safety in these applications are still under investigation.

Physical and Chemical Properties

Norsynephrine is a white to off-white crystalline powder with a molecular weight of 153.18 g/mol. It has a melting point range of 168-172°C and is soluble in water, ethanol, and methanol. The compound is stable under normal storage conditions but should be protected from light and moisture to prevent degradation. Its chemical structure features a phenethylamine backbone with a hydroxyl group at the para position and an amino group on the side chain. This structure is similar to other catecholamines like norepinephrine, giving it sympathomimetic activity.

Main Applications

Norsynephrine is primarily used in pharmaceutical research and as a dietary supplement ingredient. Its sympathomimetic properties make it of interest for studies on metabolic regulation and energy expenditure. It is also used in some weight loss and athletic performance supplements, though regulatory approval varies by region. In addition to its use in human health, norsynephrine is employed in veterinary medicine and as a research chemical in neuroscience. Its role as a neurotransmitter analog makes it valuable for studying adrenergic receptors and related pathways.

Safety and Storage

Norsynephrine should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system. Personal protective equipment (PPE) such as gloves and goggles is recommended when working with the compound. Proper ventilation is also advised to minimize inhalation risks. The compound should be stored in a cool, dry place away from light and moisture. Long-term stability can be ensured by keeping it in an airtight container. Disposal should comply with local regulations for chemical waste.

B2B Procurement Guide

When procuring norsynephrine, it is essential to verify the supplier's credentials and the purity specifications of the product. Reputable suppliers should provide certificates of analysis (CoA) and comply with regulatory requirements for the intended application. Prices typically range from $50 to $200 per gram, depending on purity and supplier. Bulk purchases may offer cost savings, but buyers should ensure that storage and handling conditions are met to maintain product integrity. Regulatory compliance, especially for pharmaceutical or supplement use, is critical.