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Norcantharidin

Updated: 2026-07-15

Overview

Norcantharidin, also known as 去甲斑蝥酸 in Chinese, is a derivative of cantharidin, a compound originally derived from blister beetles. It is widely used in the pharmaceutical industry due to its therapeutic properties. Norcantharidin is particularly noted for its role in cancer treatment and as an immune modulator. Chemically, it is a white crystalline powder that is soluble in water and various organic solvents. Its molecular structure makes it a versatile compound for further chemical modifications, enhancing its applicability in diverse industrial processes.

Physical and Chemical Properties

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Norcantharidin exhibits a melting point of approximately 160-165°C, making it stable under normal handling conditions. It is non-volatile and dissolves readily in water and ethanol, which facilitates its use in liquid formulations. The compound's stability and solubility profile are key factors in its widespread use. These properties ensure that it can be easily incorporated into various pharmaceutical formulations without significant degradation, maintaining efficacy over time.

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Main Applications

The primary application of norcantharidin is in the pharmaceutical sector, where it is used as an anti-cancer agent. It has shown promise in inhibiting tumor growth and enhancing the immune response. Beyond medicine, norcantharidin is also utilized in chemical synthesis. Its reactive sites allow for the creation of derivatives with tailored properties, expanding its utility in research and industrial applications.

Safety and Storage

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Norcantharidin should be handled with care to avoid skin or eye irritation. Proper personal protective equipment, such as gloves and goggles, is recommended when working with this compound. Storage conditions should be cool and dry, away from direct sunlight to prevent degradation. Proper labeling and secure containers are essential to ensure safety and maintain the compound's integrity over time.

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B2B Procurement Guide

When procuring norcantharidin, it is crucial to verify the supplier's credentials and request a Certificate of Analysis (COA) to confirm purity and quality. Prices can vary significantly based on purity levels and order quantities. Bulk buyers should establish long-term relationships with reputable suppliers to ensure consistent quality and reliable delivery schedules. Negotiating contracts with clear terms on quality assurance and delivery timelines can mitigate procurement risks.

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