Overview
N,N-Dimethylpropylamine (DMAPA) is an important tertiary amine with significant industrial applications. As a building block in organic synthesis, it serves as a precursor for numerous specialty chemicals. The compound's molecular structure features a three-carbon chain with a dimethylamino group, giving it both hydrophobic and hydrophilic characteristics. First synthesized in the early 20th century, DMAPA has become increasingly valuable in modern chemical manufacturing. Its reactivity makes it particularly useful for quaternization reactions and as a catalyst in various processes. The global market for DMAPA continues to grow, driven by demand from pharmaceutical and agricultural sectors.
Physical and Chemical Properties
DMAPA presents as a clear, mobile liquid with a characteristic amine odor. Its low viscosity and moderate volatility make it easy to handle in industrial settings, though proper ventilation is essential. The compound's boiling point of 110-112°C allows for relatively easy purification through distillation. Chemically, DMAPA behaves as a strong base (pKa ~10.5) and demonstrates good nucleophilicity. It readily forms salts with acids and participates in alkylation reactions. The molecule's amphiphilic nature contributes to its surfactant-like properties in certain applications. Stability-wise, DMAPA is generally resistant to hydrolysis but may degrade under extreme conditions.
Main Applications
In pharmaceuticals, DMAPA serves as a key intermediate for producing antihistamines, local anesthetics, and other active pharmaceutical ingredients (APIs). Its ability to form quaternary ammonium compounds makes it valuable for creating cationic surfactants and fabric softeners. The agrochemical industry utilizes DMAPA in synthesizing herbicides, fungicides, and plant growth regulators. Additionally, it finds use in water treatment chemicals as a corrosion inhibitor and biocide component. Recent developments have explored DMAPA's potential in specialty polymer production and as a catalyst in polyurethane formulations.
Safety and Storage
DMAPA requires careful handling due to its corrosive nature and flammability (flash point ~15°C). Storage containers should be made of stainless steel or polyethylene and kept tightly sealed to prevent moisture absorption and odor release. Secondary containment is recommended for bulk storage. Personnel must wear chemical-resistant gloves, goggles, and protective clothing when handling DMAPA. In case of spills, absorb with inert material and neutralize with dilute acid before disposal. Firefighting should use alcohol-resistant foam, dry chemical, or carbon dioxide - never use water jets which may spread the fire.
B2B Procurement Guide
When sourcing DMAPA, industrial buyers should prioritize suppliers with certified quality management systems (ISO 9001) and proper hazardous material handling certifications. Technical specifications should include purity (typically 98% min), water content (<0.5%), and residual amine content. Transportation requires UN-approved packaging (usually UN 2733, Class 8). Buyers should verify the supplier's ability to provide material safety data sheets (MSDS) and compliance certificates (REACH, TSCA). For international shipments, confirm INCOTERMS and proper hazard classification documentation. Consider establishing long-term supply agreements to mitigate price volatility.
Related Manufacturers
- 主营：防冻液、食用酒精、141B发泡剂、二甲基乙酰胺、洗网水、LG异丙醇、二氯甲烷、除胶剂、洗枪水、二乙醇胺、甘油、脱膝剂、丙三醇、三乙醇胺、增塑剂DOP、聚氨酯发泡剂、工业酒精、化白水、PMA、丙二醇、白油、清洗剂、二甲苯、无水乙醇、去渍油
- 主营：十二叔胺、十二胺、油基伯胺、二甲基丙二胺、双氢化牛脂基二甲基氯、双癸基二甲基氯化铵、十六烷基三甲基氯化铵、十二烷基三甲基氯化铵、N-甲基单乙醇胺、四甲基丙二胺、3-甲氧基丙胺、四甲基乙二胺、辛烷基二甲基叔胺、癸烷基二甲基叔胺、双辛/癸基甲基叔胺、双辛基甲基叔胺、正辛胺、1-氨基辛烷、二丙烯三胺、十八胺、椰油烷基伯胺、十二/十四叔胺、三辛烷基叔胺
- 主营：丙烯酸、醋酸丁酯、桶装散水、二异丙胺、醋酸甲酯、醋酸乙酯、碳酸乙烯酯、醋酸正丙酯
- 主营：中间体、抗氧剂、甘露糖醇、n-辛基吡咯烷酮、微量元素、光敏塑料、绿色农药、磷酸二氢铝、表面活性剂、组织改进剂、间苯二甲胺、工业级甲酸钙、工业级二甘醇、聚醋酸乙烯酯、紫外线吸收剂、活性剂耐火材料、纺织助剂增塑剂
- 主营：乙酸镁、并噻吩、三蝶烯、二甲基、硫酸锂、二乙烯、硫酸锶、肌氨酸、嘧菌酯、碳酸镁、新癸酸、赖氨酸、多佐胺、咯菌腈、乙氧基、茚三酮、咖啡酸、氟苯基、α-氟萘、羟乙基、异恶唑、2223-82-7、喹啉黄、庚二酸、虫酰肼、吡咯并
- 主营：无氟防水剂、碳六防水剂、防水剂、二甲基、水性防水剂、油性防水剂、C6防水剂、C8防水剂、C0防水剂、碳八防水剂、防水助剂、防水整理剂、开油水、稀释剂、清洗剂、天那水、洗网水、防虹吸、防泼水、动态防水、除油剂、除锈剂、飞织防水、网布防水、鞋面防水
- 主营：UV单体、阻燃剂、增塑剂、四甲基二丙烯三胺、光引发剂、生物化工中间体
- 主营：四甲基二丙烯三胺、麦芽糖酸、苯氧基环磷腈、甲巯基四氮唑
- 主营：抗氧剂BHT、苯磺酸、苯酚磺酸、N235 萃取剂、环烷酸铈、C272萃取剂、均苯四甲酸二酐、对苯乙烯磺酸钠、氟化铝、椰油酰胺丙基甜菜碱、甘油三苯甲酸酯
- 主营：磷钼酸、艾拉莫德中间体、光引发剂、6-二羟基吲哚、甲基丙二酸、甲基丙烯酸氧杂环丁烷、苯芴醇、溴芬酸钠中间体、樟脑醌、钼酸钾、丝素蛋白、盐酸胍、β-丙氨酸甲酯盐酸盐、聚二羟基吲哚、7-去氢胆固醇、甘氨胆酸钠盐、半叶素、胆固醇、2-辛基十二醇、蛋白酶K、D-荧光素钾盐、光引发剂LAP、BIS-TRIS
- 主营：聚乙烯亚胺、三甘醇二异辛酸酯3G8、三硫代碳酸钠40%、5-甲基靛红、TS-1钛硅分子筛、六氯环三磷腈、烷基苯磺酸酯、苯基次磷酸钠、甲巯咪唑、吡啶硫酮锌、焦磷酸哌嗪、热敏材料、油酸甲酯、曲酸
- 主营：叔碳酸、十八醛、溶菌酶、2-甲基丁醛、海藻糖、癸二醇、氨基丙基、氢路噻嗪、邻苯二甲、乙基碳二、羟基癸酸、正十七烷、谷胱甘肽、烷二甲醇、松果体素、vc磷酸酯镁、朱栾倍半萜、丁烷四乙酸、表面活性剂、癸烷撑二醇、缩水甘油邻、10-羟基羊蜡酸、氢氯噻嗪杂质、盐酸邻菲罗啉、壳聚糖季铵盐
- 主营：苄基三甲基氯化铵、聚苯胺、脯氨酸甲酯盐酸盐
- 主营：阳离子季铵盐、十二烷基伯胺、1-氨基辛烷、三甲基氯化铵、A8 胺辛烷、鲸熔三甲基溴化铵、十八烷基三甲基氯化铵、N-甲基单乙醇胺、十六烷基二甲基叔胺、甲基椰油酰基牛磺酸钠、氯化双癸基二甲基铵、异癸氧基丙胺、西曲溴铵、椰油胺聚氧乙烯、聚氨酯催化剂、A12、脂肪胺聚氧乙烯醚、十二烷基二亚丙三胺、椰油基仲胺、双椰油烷基胺、抗氧化剂、十八烷基伯胺、椰油二胺
- 主营：羟乙基、甜菜碱、索尔维oa、三甲基、甲基十八、基二甲基、甲基十四、氨基丙基、十八烷基、氨基辛烷、椰油酰基、抗静电剂、牛脂二胺、烷基铵内、十六叔胺、椰油二胺、西曲溴铵、油基二胺、癸撑二胺、酰胺丙基、二亚丙基、苯扎氯铵、椰油烷基、十八叔胺、十二烷基