Overview
N,N-Dimethylacetamide (DMAC) is a polar aprotic solvent with a wide range of industrial applications. It is produced by the reaction of dimethylamine with acetic anhydride or acetyl chloride. DMAC is known for its high solvency power, making it suitable for dissolving a variety of organic and inorganic compounds. DMAC is particularly valued in the pharmaceutical industry for its ability to dissolve a wide range of active pharmaceutical ingredients (APIs). Its high boiling point and thermal stability also make it a preferred choice for high-temperature reactions and processes.
Physical and Chemical Properties
DMAC is a colorless, hygroscopic liquid with a faint amine-like odor. It has a density of 0.937 g/cm³ at 25°C and a boiling point of 165°C. The compound is miscible with water and most organic solvents, including alcohols, ethers, and ketones. DMAC exhibits excellent thermal and chemical stability, which allows it to be used in high-temperature applications. Its low volatility and high flash point (70°C) contribute to its safety profile, although proper handling is still essential due to its toxicity.
Main Applications
DMAC is widely used in the pharmaceutical industry as a solvent for APIs and in the production of antibiotics, vitamins, and other drugs. Its ability to dissolve a variety of polymers makes it valuable in the production of synthetic fibers, films, and adhesives. In the textile industry, DMAC is used as a solvent in the production of polyacrylonitrile (PAN) fibers, which are precursors to carbon fibers. It is also employed in the electronics industry for the production of printed circuit boards and as a cleaning agent for delicate components.
Safety and Storage
DMAC is classified as a harmful substance and can cause skin and eye irritation upon contact. Inhalation or ingestion can lead to systemic toxicity, affecting the liver and central nervous system. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling DMAC. Storage of DMAC requires a cool, dry, and well-ventilated area away from heat sources and open flames. Containers should be tightly sealed to prevent moisture absorption and contamination. Spills should be contained and cleaned up immediately using appropriate absorbent materials.
B2B Procurement Guide
When procuring DMAC, it is essential to verify the purity and quality of the product. Suppliers should provide a Certificate of Analysis (COA) and Safety Data Sheet (SDS) to ensure compliance with regulatory standards. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be considered. Procurement professionals should also evaluate suppliers based on their reliability, delivery timelines, and after-sales support. Establishing long-term relationships with reputable suppliers can ensure consistent quality and availability of DMAC for industrial applications.
Related Manufacturers
- 主营：三氟乙酸、三氟乙酸酐、亚硝酸钠、二甲基乙酰胺、乙酸、氢氧化钠、柠檬酸、柠檬酸钠、苯甲酸钠、无水亚硫酸钠、三氯化铁、三氟乙酸乙酯
- 主营：清洗剂、工业红糖、碳酸氢钠、乙酰胺、一水柠檬酸、硫代硫酸钠、酸度调节剂、食品防腐剂、无水柠檬酸、缓冲改良剂、工业级氯化铵、食品级碳酸钠
- 主营：除垢剂、碘化钾、活性炭、二甲基硅油、n-甲基吡咯烷酮、碘试剂、氯化钠、丙三醇、缓冲剂、硫酸银、基准试剂、化学试剂、二甲亚砜、无水碳酸钠、食品添加剂、磷酸二氢钾、l(+)-抗坏血酸、无色透明液体
- 主营：二甲基乙酰胺、次氯酸钠、工业级甲酸
- 主营：乙二醇、中和剂、胶粘剂、二甲基乙酰胺、n-甲基二乙醇胺、n-甲基吡咯烷酮、环己醇、丙二醇、吐温司盘、环保溶剂、共聚维酮、丙三醇甘油、高纯度溶剂、表面活性剂、聚乙烯吡咯烷酮、山梨醇脂肪酸酯、二元酸二甲酯dbe
- 主营：壬二酸、羟乙基、三胜肽、乙酰胺、玻色因、302776-68-7、依克多因、抗坏血酸、谷胱甘肽、苯甲酸己酯、葡糖基芦丁、紫外吸收剂、辛氧基甘油、生物素三肽、乙酰基四肽、棕榈酰三肽、肉豆蔻酰五肽、植物油脂肪酸、氨基羟苯甲酰、紫外线吸收剂、维生素c乙基醚、二氢燕麦生物碱、苯乙基间苯二酚、水杨酸乙基己酯、乙基己基三嗪酮
- 主营：纯试剂、通用试剂、二氧化锰、乙酰胺、生化试剂、邻甲苯甲醛、卡尔费休试剂
- 主营：可分装样品、4-乙酰基吡啶、反-金合欢醇、乙酰胺、丁炔二酸二甲酯
- 主营：乙酰胺、对二苯甲酸二肼
- 主营：二甲基乙酰胺工业级、分析纯试剂
- 主营：聚维酮碘、磺酸二钠盐、间溴硝基苯、二甲基乙酰胺、己二酰氯、柠檬酸钴、溴化镍、氟化锌、焦锑酸钾、硫化钡、苯磺酰氯
- 主营：硫酸汞、硝酸汞、雷尼镍、二甲基乙酰胺分析纯、二十烷、丁二酸、硫化银、正己醇、硫酸镉、铋酸钠、苯甲醇、硅酸钠、正辛酸、硫酸镁、磷钨酸、滑石粉、草酸锡、蓖麻油、椰子油、钒试剂、异辛醇
- 主营：乙酸镁、并噻吩、三蝶烯、乙酰胺、硫酸锂、二乙烯、硫酸锶、肌氨酸、嘧菌酯、碳酸镁、新癸酸、赖氨酸、多佐胺、咯菌腈、乙氧基、茚三酮、咖啡酸、氟苯基、α-氟萘、羟乙基、异恶唑、2223-82-7、喹啉黄、庚二酸、虫酰肼、吡咯并
- 主营：硫化剂、阻燃剂、甘氨酸、二甲基乙酰胺、卡必醇、碳酸镁、芹菜酮、视黄醇、壬二炔、赖氨酸、藏花醛、甘羟铝、化合物、浮选剂、稀释剂、酸性红、羟乙基、芳叶油、庚二酸、庚二酮、十八烷、碳酸锌、三甲酚、甲酸钾、乙酸锌、碳酸锶
- 主营：乙酰胺、双草酸酯、二茂铁甲醛