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Nitroacetic Acid

Updated: 2026-08-20

Overview

Nitroacetic acid is an organic compound primarily used as an intermediate in chemical synthesis. It is valued in industrial applications for its reactivity and role in producing other chemicals. The compound is typically handled in controlled environments due to its corrosive nature. Industrial-grade nitroacetic acid is commonly utilized in the pharmaceutical and chemical manufacturing sectors. Its synthesis involves nitration processes, and it requires careful handling to ensure safety and efficacy in end-use applications.

Physical and Chemical Properties

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Nitroacetic acid is a colorless to pale yellow liquid with a molecular weight of 105.05 g/mol. It is soluble in water and many organic solvents, making it versatile for various chemical reactions. The compound exhibits acidic properties and is reactive under certain conditions. Its density is approximately 1.4 g/cm³, and it must be stored in a cool, dry place to prevent degradation. Due to its reactive nature, nitroacetic acid should be handled with caution, using appropriate personal protective equipment (PPE) to avoid exposure.

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Main Applications

Nitroacetic acid serves as a key intermediate in organic synthesis, particularly in the production of pharmaceuticals and specialty chemicals. Its reactivity makes it useful for introducing nitro groups into organic molecules, a common step in drug development. In addition to pharmaceuticals, nitroacetic acid is employed in the manufacture of agrochemicals and dyes. Its versatility in chemical reactions makes it a valuable component in industrial chemistry, though its use is often limited to controlled environments due to safety concerns.

Safety and Storage

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Nitroacetic acid is corrosive and requires careful handling to prevent skin, eye, and respiratory exposure. Proper PPE, including gloves, goggles, and lab coats, is essential when working with this chemical. Spills should be neutralized and cleaned up immediately. Storage conditions are critical to maintaining the stability of nitroacetic acid. It should be kept in a cool, dry, well-ventilated area, away from heat sources and incompatible materials such as strong bases and oxidizing agents. Containers must be tightly sealed to prevent moisture absorption and contamination.

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B2B Procurement Guide

When procuring nitroacetic acid, B2B buyers should prioritize suppliers with a proven track record of safety and quality compliance. Requesting a Safety Data Sheet (SDS) is essential to understand handling, storage, and disposal requirements. Pricing varies depending on quantity and supplier, so obtaining multiple quotes is advisable. Buyers should also verify the purity and concentration of the product to ensure it meets their specific application needs. Establishing long-term relationships with reliable suppliers can help secure consistent quality and competitive pricing.

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