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Napropamide

Updated: 2026-07-15

Overview

Napropamide is a selective herbicide belonging to the amide chemical class. It is primarily used in agriculture to control annual grasses and broadleaf weeds. The compound works by inhibiting root and shoot growth in susceptible plants, making it effective for pre-emergence and early post-emergence applications. Napropamide is widely used in crops such as fruits, vegetables, vineyards, and ornamentals due to its selective action and low phytotoxicity to desirable plants when used correctly. Developed in the 1970s, napropamide has become a staple in integrated weed management systems. Its chemical stability and relatively low environmental impact compared to some older herbicides contribute to its continued use. However, proper application techniques and adherence to safety guidelines are essential to maximize efficacy and minimize risks.

Physical and Chemical Properties

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Napropamide is a colorless to pale yellow crystalline solid with a molecular weight of 271.36 g/mol. It has a melting point of 75-76°C and a density of 1.18 g/cm³. The compound is slightly soluble in water (73 mg/L at 20°C) but readily dissolves in many organic solvents, including acetone, methanol, and benzene. This solubility profile influences its formulation and application methods, typically as emulsifiable concentrates or wettable powders. Napropamide exhibits low volatility and moderate persistence in soil, with a half-life ranging from weeks to months depending on environmental conditions. Its chemical stability under normal storage conditions makes it suitable for long-term use, though degradation can occur under extreme pH or UV exposure. Understanding these properties is crucial for optimizing application timing and ensuring effective weed control.

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Main Applications

Napropamide is predominantly used in agriculture for selective weed control in a variety of crops. It is particularly effective against annual grasses and broadleaf weeds in fruits (e.g., strawberries, raspberries), vegetables (e.g., tomatoes, peppers), vineyards, and ornamental plants. The herbicide is applied pre-emergence or early post-emergence, forming a protective barrier in the soil that inhibits weed seedling growth. In addition to its agricultural uses, napropamide is sometimes employed in non-crop areas such as nurseries and turf management. Its selectivity allows it to target weeds without harming established desirable plants when used according to label directions. The herbicide's versatility and effectiveness have made it a valuable tool for farmers seeking to reduce labor costs associated with manual weeding while maintaining crop yields.

Safety and Storage

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Napropamide is classified as harmful if swallowed and can cause skin and eye irritation. Appropriate personal protective equipment (PPE), including gloves, goggles, and protective clothing, should be worn during handling and application. Inhalation of dust or vapors should be avoided, and adequate ventilation is necessary in enclosed spaces. In case of exposure, immediate washing with plenty of water is recommended, and medical attention should be sought if symptoms persist. For storage, napropamide should be kept in its original container in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Proper labeling and secure storage are essential to prevent accidental misuse or environmental contamination. Disposal should comply with local regulations, avoiding release into waterways or soil where it could affect non-target organisms.

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B2B Procurement Guide

When procuring napropamide for commercial or agricultural use, several factors should be considered to ensure quality and compliance. First, verify the CAS number (15299-99-7) and purity specifications, typically ranging from 95% to 98% for technical-grade material. Reputable suppliers should provide certificates of analysis and material safety data sheets (MSDS). Regulatory compliance is critical; check that the product meets local agricultural and environmental regulations in your target market. Price negotiations should account for order volume, with bulk purchases often qualifying for discounts. Delivery terms, packaging options (e.g., 25 kg bags, custom formulations), and supplier reliability are additional considerations. Establish clear quality control protocols, including testing for consistency and contamination. Building long-term relationships with certified suppliers can ensure steady supply chains and access to technical support for optimal product use.

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