N-tert-Butyl-1H-indazole-7-carboxamide

Updated: 2026-08-04

Overview

N-tert-Butyl-1H-indazole-7-carboxamide is a chemical compound primarily used in pharmaceutical research and organic synthesis. It belongs to the indazole family, known for their potential biological activities. This compound is often utilized as an intermediate in the development of more complex molecules. The demand for N-tert-Butyl-1H-indazole-7-carboxamide is driven by its role in medicinal chemistry, where it serves as a building block for drug discovery. Its molecular structure allows for modifications that can lead to the creation of novel therapeutic agents.

Physical and Chemical Properties

N-tert-Butyl-1H-indazole-7-carboxamide is typically found as a white to off-white powder. It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and methanol, which makes it suitable for various chemical reactions. The compound's molecular weight is 217.27 g/mol, and it has the formula C12H15N3O. Stability is a key feature of this compound under recommended storage conditions. However, it should be protected from light and moisture to maintain its integrity over time. Detailed physical properties like melting and boiling points are not widely documented.

Main Applications

The primary application of N-tert-Butyl-1H-indazole-7-carboxamide is in the pharmaceutical industry, where it is used as an intermediate in drug synthesis. Its structure is valuable for creating compounds with potential therapeutic effects, particularly in the development of kinase inhibitors and other small-molecule drugs. Beyond pharmaceuticals, this compound is also employed in academic and industrial research for organic synthesis projects. Its versatility makes it a useful tool for chemists exploring new chemical entities and reaction pathways.

Safety and Storage

Handling N-tert-Butyl-1H-indazole-7-carboxamide requires standard laboratory safety practices. It is advisable to use personal protective equipment, including gloves and safety goggles, to avoid skin contact and inhalation. The compound should be stored in a cool, dry place, away from direct light and moisture. In case of exposure, rinse the affected area with plenty of water and seek medical advice if necessary. Proper disposal methods should be followed to minimize environmental impact, adhering to local regulations for chemical waste.

B2B Procurement Guide

When procuring N-tert-Butyl-1H-indazole-7-carboxamide, it is essential to verify the supplier's credentials and the purity of the product. Reputable suppliers should provide certificates of analysis (CoA) to confirm the compound's quality. Buyers should also consider the quantity needed, as prices may vary based on volume. Lead times and shipping conditions are other critical factors. Ensure that the compound is shipped under appropriate conditions to maintain its stability. Establishing long-term relationships with reliable suppliers can help secure consistent quality and competitive pricing.