Overview
N-Hydroxyisobutyramide is an organic compound primarily used as an intermediate in pharmaceutical synthesis. It is a derivative of isobutyramide with a hydroxyl group attached to the nitrogen atom, enhancing its reactivity in certain chemical reactions. This compound is valued in industrial chemistry for its role in producing more complex molecules. Its stability and solubility make it a versatile reagent in laboratory and manufacturing settings.
Physical and Chemical Properties
N-Hydroxyisobutyramide appears as a white crystalline powder with a molecular weight of 103.12 g/mol. It is soluble in water and most organic solvents, which facilitates its use in various reaction conditions. The compound exhibits moderate thermal stability, with a melting point around 80-85°C. Its hydroxyl group contributes to its mild reducing properties, making it useful in specific synthetic pathways.
Main Applications
N-Hydroxyisobutyramide is primarily employed in the pharmaceutical industry as a building block for active pharmaceutical ingredients (APIs). It serves as a precursor in the synthesis of various drugs and agrochemicals. In addition to pharmaceuticals, it finds use in organic synthesis laboratories for constructing complex molecular architectures. Its reactivity is leveraged in reactions where mild reducing agents are required.
Safety and Storage
While not classified as highly hazardous, N-Hydroxyisobutyramide requires standard chemical handling precautions. Personal protective equipment (PPE) including gloves and safety goggles should be worn when handling this compound. The material should be stored in tightly sealed containers in a cool, dry environment away from incompatible substances. Proper ventilation should be maintained in storage and handling areas to prevent dust accumulation.
B2B Procurement Guide
When sourcing N-Hydroxyisobutyramide for commercial purposes, buyers should prioritize suppliers who provide detailed certificates of analysis (CoA) to verify purity and composition. Consider minimum order quantities and bulk pricing structures when negotiating with suppliers. Quality control measures should include independent testing of samples to ensure consistency between batches.
Related Manufacturers
- 主营：联吡啶、甘氨酰、丁烯酸、八(6-溴、阻燃剂、酸性橙、西瓜酮、硫酸锰、氯丁烷、甲醇钙、聚合物、肌氨酸、咯喹酮、烷硫酮、磷酸铵、锑酸钠、双噻吩、磷酸铁、中性红、碳酸镍、磷酸铜、异丁酯、氨丁基、浅铬黄
- 主营：间苯二甲胺、硫化砷、808洗涤剂胰加漂T、4-叔丁基苯基硼酸、N-二甲基乙二胺、N-甲基烟酰胺、顺式-2、6-二甲基、4'-二羟基二苯、1-硫代甘油、己二酸双(2-丁氧基、N-乙酰基己内酰胺、增甘膦、富马酸、霜脲氰、氧化铋、三甲氧基硅烷、紫外线吸收剂、八钼酸铵、十二烷基苯磺酸钠、聚乙烯醇、邻苯二甲酸丁苄酯、甲基环戊烯醇酮、二壬基萘磺酸、邻仲丁基苯酚
- 主营：溴苯腈、乙基己酸锌、荧光增白剂、羟基、羟乙基纤维素、乙酰乙酸乙酯
- 主营：阻燃剂、茄边碱、紫苏葶、075-68-6)、9-溴菲(、肌氨酸、敌螨普、丁酸铝、碳酸镁、肉桂醛、乙烯醇、乙氧基、吡唑胺、对氨基、叶绿素、氟苯基、特丁津、羟乙基、噻虫啉、仲丁威、黄岑素、氧化铕、硫化环、呋虫胺、羰基双
- 主营：二乙基、仲辛酮、阻燃剂、羟基、溴磷松、玉米素、基嘧啶、特乐酯、多果定、阿螨特、甲硫基、氮化镨、草除灵、聚合物、橙叶油、灭虫隆、三甲胺、敌螨普、育畜磷、禾草灵、溶剂绿、聚甘油、惕格酸、碳酸镍、肉桂醛、分散蓝
- 主营：正辛胺、柠檬酸、尿嘧啶、15397-15-6、119736-16-2、4-嘧啶酮、923289-21-8、152628-02-9、苯甲酰胺、2346620-55-9、抗皱素、绿原酸、异丁基、三辛胺、双醚芴、姜黄素、角鲨烯、精磺胺、蒜氨酸、九甘醇、氟苯基、比卡鲁胺、四氢嘧啶、氨基二环、麦角硫因
- 主营：苯肼、氯甲基苯乙烯、无水氯化锂、4-二氢吡喃、4-溴靛红、四羟基二硼、丙酰乙酸甲酯、邻硝基苯磺酰氯、碘甲烷、亚磷酸三苯酯、苯并噻唑、苄胺、苯基锂、叔丁醇钾、三丁基膦