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N-Ethylphthalimide

Updated: 2026-08-21

Overview

N-Ethylphthalimide is an organic compound belonging to the class of phthalimides. It is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty polymers. The compound is characterized by its white crystalline appearance and stability under normal conditions. Its molecular structure includes a phthalimide ring substituted with an ethyl group, which enhances its reactivity in various chemical reactions. This makes it a valuable building block in organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs).

Physical and Chemical Properties

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N-Ethylphthalimide is a white to off-white crystalline powder with a molecular weight of 175.18 g/mol. It has a melting point of approximately 72-75°C, making it stable at room temperature. The compound is soluble in common organic solvents such as ethanol and acetone but exhibits limited solubility in water. Chemically, N-Ethylphthalimide is relatively stable but can decompose under extreme conditions, such as exposure to strong acids or bases. Its stability and solubility profile make it suitable for use in various industrial applications, including as a reagent in organic synthesis.

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Main Applications

N-Ethylphthalimide serves as a key intermediate in the production of pharmaceuticals, where it is used to synthesize active ingredients for medications. It is also employed in the agrochemical industry for the development of pesticides and herbicides. In addition, the compound finds use in material science, particularly in the synthesis of specialty polymers and resins. Its reactivity and stability make it a versatile component in organic chemistry, enabling the creation of complex molecules for industrial and research purposes.

Safety and Storage

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When handling N-Ethylphthalimide, it is essential to follow safety protocols to minimize exposure. The compound may cause irritation upon contact with skin, eyes, or respiratory system. Always use personal protective equipment (PPE), including gloves and goggles, and work in a well-ventilated area. Storage should be in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are recommended to prevent degradation. In case of accidental exposure, rinse affected areas with water and seek medical attention if necessary.

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B2B Procurement Guide

For B2B buyers, it is crucial to verify the CAS number (85-40-5) and purity specifications when purchasing N-Ethylphthalimide. Suppliers typically offer the compound in various grades, with pharmaceutical-grade being the highest purity. Bulk orders often qualify for discounts, so buyers should inquire about volume pricing. Additionally, consider suppliers with certifications such as ISO or GMP to ensure product quality. Shipping and storage conditions should also be confirmed to maintain the compound's integrity during transit.

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