Monkey C4-binding protein

Updated: 2026-09-17

Overview

Monkey C4-binding protein is a specialized protein that plays a crucial role in the regulation of the complement system, a part of the immune response. It binds to complement component C4, modulating its activity and preventing excessive immune reactions. This protein is primarily used in biomedical research to study immune system mechanisms and develop therapeutic interventions. Researchers value Monkey C4-binding protein for its specificity and relevance in studying primate immune responses. It is often sourced from non-human primates, making it a critical tool for translational research aiming to bridge findings from animal models to human applications.

Physical and Chemical Properties

Monkey C4-binding protein is typically supplied as a lyophilized powder or in a liquid buffer solution. Its solubility in aqueous solutions makes it suitable for various experimental setups. The protein's stability depends on proper storage conditions, typically requiring temperatures at or below -20°C to maintain its functional integrity. The protein's molecular weight and exact structure may vary slightly depending on the source species and purification methods. Analytical techniques such as SDS-PAGE and mass spectrometry are commonly used to verify its purity and confirm its identity before use in sensitive experiments.

Main Applications

The primary application of Monkey C4-binding protein lies in immunology research, particularly in studies focusing on the complement system. It is used to investigate the regulation of immune responses, the pathogenesis of autoimmune diseases, and the development of complement-targeted therapies. In drug development, this protein serves as a valuable reagent for screening potential inhibitors or modulators of the complement cascade. Its use in preclinical studies helps assess the safety and efficacy of new immunotherapeutic candidates before human trials.

Safety and Storage

Handling Monkey C4-binding protein requires standard laboratory precautions, including the use of gloves, lab coats, and eye protection. Although not classified as highly hazardous, direct contact with skin or mucous membranes should be avoided to prevent potential irritation or allergic reactions. Proper storage is critical to maintain the protein's stability and functionality. Lyophilized forms should be reconstituted with appropriate buffers and aliquoted to minimize repeated freeze-thaw cycles, which can degrade the protein. Long-term storage at -80°C is recommended for extended preservation.

B2B Procurement Guide

When procuring Monkey C4-binding protein, buyers should prioritize suppliers with a proven track record in providing high-quality biological reagents. Key considerations include the protein's purity (typically verified by gel electrophoresis or HPLC), concentration, and the absence of contaminants such as endotoxins. Purchasers should also evaluate the supplier's documentation, including certificates of analysis and detailed product specifications. Bulk buyers may negotiate pricing, but should ensure that storage and shipping conditions meet the protein's requirements to avoid compromising its quality upon delivery.