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Methylzinc

Updated: 2026-07-15

Overview

Methylzinc, also known as dimethylzinc, is an organometallic compound that plays a significant role in organic synthesis and materials science. It is a highly reactive and pyrophoric liquid, meaning it ignites spontaneously upon exposure to air. Due to its reactivity, methylzinc is typically handled under inert atmospheres such as nitrogen or argon. This compound is widely used as a methylating agent in organic reactions and is particularly valuable in the production of semiconductors and other advanced materials. Its reactivity with water and air necessitates careful handling and storage procedures to ensure safety and maintain its efficacy.

Physical and Chemical Properties

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Methylzinc is a colorless to light yellow liquid with a density of 1.386 g/cm³. It has a low boiling point of 46°C and a melting point of -42°C, making it volatile at room temperature. The compound is highly soluble in organic solvents but reacts violently with water, releasing methane gas and forming zinc hydroxide. Its pyrophoric nature means it can ignite spontaneously when exposed to air, necessitating storage under inert gases. Methylzinc is also a strong reducing agent, which makes it useful in various chemical reactions where electron donation is required. These properties underscore the importance of proper handling and storage to prevent accidents.

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Main Applications

Methylzinc is primarily used in organic synthesis as a methylating agent, transferring methyl groups to other molecules. It is particularly valuable in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Additionally, it serves as a precursor in the production of zinc oxide thin films, which are used in semiconductors and optoelectronic devices. In the semiconductor industry, methylzinc is employed in metal-organic chemical vapor deposition (MOCVD) processes to create high-purity zinc-containing materials. Its ability to form stable complexes with other organometallic compounds further enhances its utility in advanced material synthesis. These applications highlight its importance in both academic research and industrial manufacturing.

Safety and Storage

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Due to its pyrophoric nature, methylzinc must be handled with extreme caution. It should only be used in well-ventilated fume hoods and under an inert atmosphere to prevent contact with air or moisture. Personal protective equipment (PPE), including gloves, goggles, and flame-resistant clothing, is essential when working with this compound. Storage conditions are critical to maintaining the stability of methylzinc. It should be kept in sealed containers under an inert gas, such as nitrogen or argon, and stored in a cool, dry place away from heat sources and oxidizing agents. Proper disposal methods must also be followed to mitigate environmental and safety risks.

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B2B Procurement Guide

When procuring methylzinc, B2B buyers should prioritize suppliers who provide detailed handling and storage instructions. Verification of the CAS number (544-97-8) is essential to ensure the correct product is being purchased. Buyers should also inquire about the purity level, as higher purity grades are often required for sensitive applications like semiconductor manufacturing. Price ranges can vary significantly based on purity and supplier, with common estimates ranging from $200 to $500 per gram. Bulk purchases may offer cost savings, but buyers must ensure they have the necessary infrastructure to safely store and handle larger quantities. Establishing long-term relationships with reputable suppliers can also help secure consistent quality and reliable delivery schedules.

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