Overview
Methylpropionamide, also known as N-Methylpropionamide, is an organic compound with the molecular formula C4H9NO. It is a colorless to pale yellow liquid with a mild odor and is widely used in various industrial applications due to its solvent properties and reactivity as an amide. The compound is primarily utilized as an intermediate in pharmaceutical synthesis and agrochemical production. Methylpropionamide is valued for its high polarity and ability to dissolve a wide range of substances, making it a versatile component in chemical processes. Its synthesis typically involves the reaction of propionyl chloride with methylamine, followed by purification to achieve the desired purity levels.
Physical and Chemical Properties
Methylpropionamide exhibits a density of approximately 0.934 g/cm³ at 25°C and a boiling point around 170°C. It is soluble in water, ethanol, and most organic solvents, which enhances its utility as a solvent in various chemical reactions. The compound's melting point is approximately -20°C, and it remains stable under normal storage conditions. The key chemical properties of methylpropionamide include its high polarity and reactivity as an amide, which make it suitable for use in nucleophilic substitution reactions and as a precursor in the synthesis of more complex molecules. Its stability and solubility profile contribute to its widespread use in industrial and laboratory settings.
Main Applications
Methylpropionamide is predominantly used as an intermediate in the pharmaceutical industry, where it serves as a building block for the synthesis of active pharmaceutical ingredients (APIs). Its role in agrochemical production is also significant, as it is involved in the creation of pesticides and herbicides. In addition to its applications in pharmaceuticals and agrochemicals, methylpropionamide is employed as a solvent in various industrial processes. Its ability to dissolve a wide range of substances makes it a valuable component in coatings, adhesives, and other chemical formulations. The compound's versatility ensures its continued demand in multiple sectors.
Safety and Storage
Methylpropionamide should be handled with care to avoid inhalation, skin contact, or ingestion. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is recommended when working with this chemical. Proper ventilation is essential to minimize exposure to vapors. Storage conditions for methylpropionamide include keeping the compound in a cool, dry, well-ventilated area away from heat sources and open flames. Containers should be tightly sealed to prevent moisture absorption and contamination. In case of spills, absorb the material with an inert substance and dispose of it according to local regulations.
B2B Procurement Guide
When procuring methylpropionamide, B2B buyers should prioritize suppliers who adhere to stringent quality and safety standards. Verification of the CAS number (1187-58-2) and purity specifications is crucial to ensure the product meets the required application standards. Buyers should also consider the packaging options, as methylpropionamide is typically supplied in drums or intermediate bulk containers (IBCs). Pricing varies based on purity and quantity, with reference prices ranging from approximately $50 to $100 per kilogram. Establishing long-term relationships with reputable suppliers can help secure consistent quality and competitive pricing.
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