Overview
Methylamine is one of the simplest organic amines, consisting of a methyl group attached to an amino group. It exists as a gas at room temperature but is commonly handled as a liquid under pressure or in aqueous solutions. As a building block in organic chemistry, it plays a critical role in numerous industrial processes. The compound occurs naturally in some plants and animals, but industrial production typically involves the reaction of methanol with ammonia over a catalyst. Global production exceeds 1 million tons annually, with major manufacturing facilities located in North America, Europe, and Asia.
Physical and Chemical Properties
Methylamine exhibits typical amine properties, including alkalinity and the ability to form salts with acids. The pure compound has a sharp, fishy odor detectable at low concentrations. Its vapor is heavier than air and may travel along the ground to distant ignition sources. Chemically, methylamine is a good nucleophile and participates in various reactions including alkylation, acylation, and condensation. It forms stable complexes with transition metals and serves as a ligand in coordination chemistry. The aqueous solution shows basic properties with a pKb of approximately 3.36.
Main Applications
The pharmaceutical industry accounts for about 40% of methylamine consumption, where it serves as a precursor to numerous drugs including ephedrine, theophylline, and various local anesthetics. In agriculture, it's used to produce herbicides like atrazine and fungicides such as carbendazim. Other significant applications include the production of N-methyl-2-pyrrolidone (NMP), a versatile solvent, and various surfactants. The rubber industry utilizes methylamine derivatives as vulcanization accelerators. Emerging uses include battery electrolyte formulations and carbon capture technologies.
Safety and Storage
Methylamine presents multiple hazards including flammability, corrosivity, and toxicity. Storage tanks should be grounded and bonded, with proper pressure relief systems. Facilities must have adequate ventilation and gas detection systems. Personnel handling methylamine should wear chemical-resistant gloves, face shields, and respiratory protection when appropriate. In case of leaks, neutralize small spills with dilute acid solutions. Large spills may require professional hazmat response due to the risk of vapor cloud formation and potential for explosions.
B2B Procurement Guide
When sourcing methylamine, buyers should verify supplier compliance with regional chemical regulations (REACH, TSCA, etc.). Technical specifications should include purity (typically 40% or 99%), water content, and impurity profiles. Transport logistics require special consideration - aqueous solutions are generally safer to handle than anhydrous methylamine. For international shipments, verify that carriers have proper UN certification for Class 2.1 flammable gases. Some jurisdictions may require special permits for storage above certain quantities.
Related Manufacturers
- 主营：全氟三丁胺、木质素、吉氏色素
- 主营：有机原料、中间体、香精香料、催化剂、有机硅、表面活性剂
- 主营：定量勺、硫酸铵、硫酸银、甲基红、四甲基、锗试剂、层析柱、大豆油、指示剂、枪状镊、软脂酸、开口器、角鲨烯、玫瑰红、进样针、高硼硅、丙烯酸、乙酸铜、甲酸铵、乳酸钙、乙酸钾、氧化锌、乙醛酸、硫酸锌、丙二醇
- 主营：大小化工试剂
- 主营：二甲基亚磺酰亚胺、对二氧环己酮PDO、聚对二氧环己酮PPDO、乙交酯
- 主营：1-苯丙醇、1-萘甲醚、科隆试剂、2-甲基吡嗪、罗恩试剂、金刚烷醇、1-溴十八烷、2-恶唑烷酮、1-甲酰哌啶、2-氟苯甲醛、2-氮己环酮、1-溴金刚烷、阿拉丁试剂、麦克林试剂、科密欧试剂、大小化工试剂
- 主营：碳酸铝、防霉剂、氯化铋、二甲基亚枫、氮化硅、破乳剂、硅酸镁、磷酸铝、化学试剂、抗静电剂、乙酸乙酯、氢氧化镁、焦磷酸钠、干燥通风、次磷酸镁、氯化氢乙醇、氯化氢甲醇、聚丙烯酸钾、闪点提高剂、柴油降凝剂、硫代硫酸铵、聚丙烯酰胺、多聚磷酸钠、25公斤纸板桶、硫代乙醇酸钠、高分子絮凝剂
- 主营：氯化钠、除味剂、聚乙烯胺、醋酸亚铁、聚乙烯亚胺、聚酰亚胺树脂、二羟醋酸、肌氨基酸、聚乙烯铵、米诺地尔、一水肌酸、树苔浸膏、2-丁二醇、纳米勃姆石、花椒油树脂、醋酸氯己定、糊状叶绿素、无味子醇甲、三硬脂酸铝、胡椒基丁醚、全氟三丁胺、5-甲氧基色胺、人造康酿克油、有机硅季铵盐、氯化十六吡啶
- 主营：吡咯酯、藜芦酮、麦芽酚、6-甲基香豆素、铃兰醛、吴茱萸碱、聚谷氨酸、3-吲哚甲醛、农药中间体、7-羟基香豆素、4-羟基香豆素、6-氰基-2-萘酚、5-甲氧基色胺、β-氯代苯乙烷
- 主营：保护剂、碘化钾、抗氧剂、甲基丙烯酰氯、碘化钠、固体粉末、无味液体、迷迭香素、白色粉末、草酸钛钾、碱式碳酸铜、荧光增白剂、羟乙基磺酸钠、4 - 二氟苯胺、4'- 羟基苯丁酮、二碳酸二叔丁酯、原异丁酸三甲酯
- 主营：乙醇钾、烯丙基碘、异戊酰氯、甲基亚磺酸钠试剂、癸二酰氯、偏钒酸钾、丙二酰氯、糠基硫醇、硫代乳酸、1-乙基哌啶、n-丁基苯胺、2-环己烯酮、2-乙基吡啶、4-乙基吡啶、4-碘硝基苯、3-碘硝基苯、二丙基硫醚、碘代仲丁烷、间硝基苯胺、硫氰酸苄酯、硫氰酸甲酯、分析纯试剂、环氧溴丙烷、乙酸间甲苯酯、氯仿酸氯甲酯、重氮乙酸乙酯
- 主营：DTT、DMAA、联枯、三羟甲基氨基甲烷、三羟甲基氨基甲烷盐酸盐、5-二甲基海因、N-甲基吡咯烷酮、联苯二酚、DBU、对溴苯氧乙酸、6-kt、赤霉素、敌草隆、丙炔氟草胺、啶嘧磺隆、甲嘧磺隆、噻吩磺隆、三氟啶磺隆、N-二乙基丙炔胺、乙酰丙酮铝、异氰尿酸三缩水甘油酯、甲哌鎓、氯酯磺草胺
- 主营：氟苯基、n-氯乙酰、二氧杂葵、氟甲基吡嗪、氟喹唑啉、氮杂吲哚、正亮氨酸、乙氧基杯、邻苯二甲、氟苯氧基、羟基吡啶、丁基二氟、乙酰基对、溴异喹啉、噻唑羧酸、氟苯甲酸、异丙氧羰基、异硫氰酸酯、酯苯磺酸盐、甲氧基溴苄、苄氧基羰基、丝氨酸苄酯、硫氰酸苯酯、氧胆酸中间体、高丝氨酸内酯
- 主营：二乙基、氯乙酯、异戊酸、甲基亚磺酰、阻燃剂、钼酸铵、2-庚醇(、赤松素、甲酚钛、檀香醇、甲硫基、甲醇钙、氮化镨、氮化镱、氰酸银、氮化镝、磷酸铵、油酸钠、丙酸铵、氮化锗、植物醇、降莰烷、乙烯醇、尼海屈、隐花青、甲酰胺
- 主营：水杨甙、吡喃灵、乙酸镍、甲基亚丙基、酸性橙、硫酸锑、硫酸锂、二乙烯、硫酸锰、075-68-6)、甲醇钙、酸性紫、羟钴胺、敌螨普、磷酸铵、硫化褐、丙酸铵、中性红、碳酸镍、赖氨酸、柚皮素、乙氧基、氟苯基、酸性红、羟乙基、白碳黑