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Methylhydroxylamine

Updated: 2026-07-15

Overview

Methylhydroxylamine is an organic compound primarily used in chemical synthesis and pharmaceutical applications. It is a derivative of hydroxylamine with a methyl group attached, making it a versatile reagent in organic chemistry. The compound is commonly employed as a nucleophile or reducing agent in various reactions. Due to its reactivity, methylhydroxylamine is often handled in controlled environments. It is available in liquid form and is soluble in water and many organic solvents. Its applications range from laboratory research to industrial-scale chemical production.

Physical and Chemical Properties

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Methylhydroxylamine is a colorless liquid with a molecular weight of 47.05 g/mol. It has a density of approximately 0.94 g/cm³ and a boiling point around 48-50°C. The compound is hygroscopic, meaning it absorbs moisture from the air, which can affect its stability and handling. Chemically, methylhydroxylamine acts as a nucleophile, participating in reactions such as the formation of oximes and other derivatives. It is also a reducing agent, capable of donating electrons in redox reactions. These properties make it valuable in synthetic chemistry.

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Main Applications

Methylhydroxylamine is widely used in the pharmaceutical industry as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is also employed in the production of agrochemicals, dyes, and other specialty chemicals. In research laboratories, methylhydroxylamine serves as a reagent for modifying biomolecules and studying reaction mechanisms. Its ability to form stable complexes with metals and other compounds expands its utility in various chemical processes.

Safety and Storage

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Methylhydroxylamine is an irritant and should be handled with care. Proper personal protective equipment (PPE), including gloves and goggles, is essential. The compound should be stored in a cool, dry place, away from oxidizing agents and sources of ignition. Spills should be cleaned up immediately using appropriate absorbent materials. Disposal must comply with local regulations to minimize environmental impact. Always consult safety data sheets (SDS) for detailed handling instructions.

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B2B Procurement Guide

When procuring methylhydroxylamine, buyers should prioritize purity, supplier reliability, and compliance with safety standards. Verify the CAS number (593-75-9) to ensure the correct compound is being sourced. Request certificates of analysis (CoA) to confirm purity and quality. Bulk purchases may require negotiations on pricing and delivery terms. Establish long-term relationships with reputable suppliers to ensure consistent supply and quality.

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