Methylcyclohexanone

Updated: 2026-09-12

Overview

Methylcyclohexanone is an organic compound belonging to the cyclohexanone family, characterized by a six-membered carbon ring with a ketone functional group and a methyl substituent. It exists as two isomers (2- and 3-methylcyclohexanone), with the 2-isomer being more industrially prevalent. The compound is produced through catalytic hydrogenation of cresols or oxidation of methylcyclohexane. As a versatile solvent, it offers balanced evaporation rates and solvency power for synthetic resins, making it valuable in coatings and adhesive formulations. Its chemical structure also allows use as a building block in pharmaceutical and agrochemical synthesis, where it serves as a precursor for more complex molecules.

Physical and Chemical Properties

Methylcyclohexanone is a mobile liquid with a characteristic ketone-like odor, moderately volatile with a vapor pressure of about 2 mmHg at 20°C. Its density is lower than water (0.92 g/cm³), and it exhibits typical ketone reactivity including nucleophilic addition reactions. The boiling point range of 165-170°C makes it suitable for high-temperature applications. Chemically, it undergoes reactions typical of aliphatic ketones, including condensation, reduction to alcohols, and oxidation under vigorous conditions. The methyl group introduces slight steric hindrance compared to unsubstituted cyclohexanone. It forms azeotropes with water and common organic solvents, which is relevant for solvent recovery processes in industrial settings.

Main Applications

In industrial applications, methylcyclohexanone primarily functions as a medium-boiling solvent for cellulose esters, vinyl resins, and alkyd coatings. Its balanced evaporation rate makes it particularly useful in automotive and industrial paint formulations where it contributes to flow control and gloss development. The chemical industry utilizes it as an intermediate for synthesizing pharmaceuticals like steroids and agricultural chemicals. In fragrances, it serves as a modifying agent due to its mild, camphoraceous odor. Emerging applications include use as a solvent for specialty polymer processing and as a component in lithium-ion battery electrolytes, where its stability properties are being investigated.

Safety and Storage

As a flammable liquid (Flash point: 48°C), methylcyclohexanone requires storage in approved flammable liquid cabinets or well-ventilated areas, away from oxidizers and ignition sources. Containers should be grounded during transfer to prevent static discharge. Secondary containment is recommended for bulk storage. Exposure controls include local exhaust ventilation and chemical-resistant gloves (nitrile or neoprene). The substance may cause eye irritation and central nervous system depression at high vapor concentrations. Spills should be contained with inert absorbents and disposed according to local regulations. Firefighting requires alcohol-resistant foam, dry chemical, or CO2 extinguishers.

B2B Procurement Guide

Industrial buyers should specify technical grade (≥98% purity) with moisture content below 0.5% for most applications. Pharmaceutical-grade material requires additional testing for heavy metals and residual solvents. Common packaging includes 200L steel drums or isotanks for bulk quantities (1-20 metric tons). Key supplier qualifications include ISO 9001 certification, REACH compliance documentation, and batch-specific Certificates of Analysis. Pricing is typically volume-dependent, with discounts available for contract quantities. Logistics considerations include UN packaging group III compliance for transportation and proper hazard communication labeling. Asian and European producers dominate supply, with lead times of 2-4 weeks for spot orders.