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Methyl vanillate[2]

Updated: 2026-09-11

Overview

Methyl vanillate is an organic compound classified as an aromatic ester. It is derived from vanillic acid and is commonly used in the flavor and fragrance industry due to its sweet, vanilla-like aroma. The compound is synthesized through esterification reactions and is valued for its stability and versatility in various applications. In addition to its use in perfumery, methyl vanillate serves as an intermediate in pharmaceutical manufacturing. Its chemical structure allows it to participate in further synthetic processes, making it a valuable building block in organic chemistry.

Physical and Chemical Properties

Methyl vanillate appears as a white to off-white crystalline powder with a characteristic vanilla scent. It has a molecular weight of 182.17 g/mol and a melting point range of 62-65°C. The compound is soluble in organic solvents like ethanol and methanol but exhibits limited solubility in water. Key chemical properties include its ester functional group, which contributes to its reactivity in hydrolysis and transesterification reactions. The presence of a methoxy and hydroxyl group on the benzene ring enhances its aromatic properties, making it suitable for flavor and fragrance applications.

Main Applications

The primary use of methyl vanillate is in the flavor and fragrance industry, where it imparts a sweet, vanilla-like note to products. It is often incorporated into perfumes, cosmetics, and food flavorings to enhance sensory appeal. In pharmaceuticals, methyl vanillate acts as an intermediate in the synthesis of more complex molecules. Its stability and reactivity make it a preferred choice for producing active pharmaceutical ingredients (APIs) and other fine chemicals.

Safety and Storage

Methyl vanillate should be handled with care to avoid inhalation or skin contact. Proper personal protective equipment (PPE), such as gloves and goggles, is recommended during handling. The compound should be stored in a cool, dry place, away from direct sunlight and incompatible materials. In case of accidental exposure, rinse affected areas with water and seek medical attention if necessary. Always refer to the material safety data sheet (MSDS) for detailed safety instructions.

B2B Procurement Guide

When procuring methyl vanillate, it is essential to verify the CAS number (3943-74-6) and purity specifications to ensure product quality. Suppliers may offer varying grades, so clarify the intended use with the vendor. Bulk purchases often come with cost advantages, so negotiate pricing for large orders. Additionally, consider the supplier's reputation, lead times, and compliance with industry standards to ensure a smooth procurement process.

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