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Methyl Palmitate Reference Standard

Updated: 2026-07-15

Overview

Methyl palmitate reference standard is a chemically pure form of methyl palmitate, primarily used for calibration and quality control in analytical laboratories. It serves as a critical tool in gas chromatography (GC) and high-performance liquid chromatography (HPLC) to ensure accurate measurements of fatty acid methyl esters (FAMEs). This compound is synthesized through the esterification of palmitic acid with methanol, resulting in a stable and well-characterized product. Its consistent properties make it indispensable in pharmaceutical, food, and environmental testing.

Physical and Chemical Properties

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Methyl palmitate is a long-chain fatty acid ester with a molecular weight of 270.45 g/mol. It typically appears as a colorless to pale yellow liquid or solid, depending on temperature. The compound has a density of 0.85-0.87 g/cm³ and a melting point of 28-30°C. Its solubility profile makes it suitable for use in organic solvents like ethanol and ether, though it is insoluble in water. The ester is relatively stable under normal conditions but should be protected from prolonged exposure to light and oxidizing agents to maintain purity.

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Main Applications

The primary use of methyl palmitate reference standard is in analytical chemistry, where it acts as a calibration standard for chromatographic methods. It is essential for quantifying fatty acid content in oils, fats, and biological samples. In pharmaceuticals, it helps validate methods for drug formulation and quality control. Additionally, researchers use it in metabolic studies and as a substrate for enzymatic reactions. Its role in biodiesel research is also notable, as it aids in analyzing fuel composition and performance.

Safety and Storage

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While methyl palmitate is not highly hazardous, proper safety measures should be followed. Avoid direct skin contact and inhalation of dust or vapors. Use gloves, goggles, and lab coats when handling. Store the compound in a tightly sealed container in a cool, dry place, away from light and incompatible materials like strong oxidizers. Stability is typically guaranteed for up to two years when stored under recommended conditions, but always check the manufacturer's guidelines.

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B2B Procurement Guide

When procuring methyl palmitate reference standard, prioritize suppliers with ISO or GMP certifications to ensure quality. Request a certificate of analysis (CoA) detailing purity, batch number, and testing methods. Compare prices from multiple vendors, but avoid compromising on purity (≥98% is standard for reference materials). Bulk purchases may offer cost savings, but verify storage capacity to prevent degradation. Lead times can vary, so plan orders in advance for critical projects.

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