Overview
Methyl trans-p-Coumarate is a derivative of p-coumaric acid, commonly used as a reference standard in analytical chemistry and pharmaceutical research. It is known for its role in studying phenolic compounds and their biological activities. The compound is synthesized through esterification of trans-p-coumaric acid with methanol. Its high purity and stability make it a reliable standard for HPLC, LC-MS, and other analytical techniques.
Physical and Chemical Properties
Methyl trans-p-Coumarate is a white to off-white crystalline powder with a molecular weight of 178.18 g/mol. It has a melting point of approximately 125-128°C and is soluble in common organic solvents like ethanol and methanol. Its chemical structure includes a phenolic hydroxyl group and an ester functional group, which contribute to its reactivity and solubility properties. The compound is stable under recommended storage conditions but may degrade if exposed to prolonged light or moisture.
Main Applications
This compound is primarily used as a reference standard in pharmaceutical and biochemical research. It helps in the quantification and identification of phenolic compounds in natural products and herbal extracts. Additionally, Methyl trans-p-Coumarate is employed in studies related to antioxidant activity, anti-inflammatory effects, and other biological properties of phenolic acids. Its role in metabolic pathway research is also noteworthy.
Safety and Storage
Proper handling of Methyl trans-p-Coumarate requires the use of personal protective equipment (PPE), including gloves and safety goggles. Avoid inhalation or direct contact with skin and eyes. For storage, keep the compound in a cool, dry place away from light and moisture. Ensure the container is tightly sealed to prevent contamination and degradation. Dispose of waste material in accordance with local regulations.
B2B Procurement Guide
When procuring Methyl trans-p-Coumarate, verify the supplier's reputation and request a Certificate of Analysis (CoA) to confirm purity and quality. Compare prices from multiple vendors, as costs can vary significantly based on purity and quantity. Consider bulk purchases for cost savings, but ensure proper storage facilities are available. Reliable suppliers often provide technical support and documentation, which can be crucial for compliance and research accuracy.
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