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Methyl bromoacetate

Updated: 2026-07-29

Overview

Methyl Bromoacetate is an organic compound commonly used as a reagent in various chemical syntheses. It is a colorless to pale yellow liquid with a pungent odor. The compound is highly reactive, making it valuable in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity, Methyl Bromoacetate is often employed in alkylation reactions and as a building block in organic chemistry. Its versatility and effectiveness in these applications have made it a staple in many industrial processes.

Physical and Chemical Properties

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Methyl Bromoacetate has a molecular weight of 152.98 g/mol and a density of 1.65 g/cm³. It boils at 145-146°C and melts at -38°C. The compound is soluble in most organic solvents but only slightly soluble in water. Its key chemical properties include high reactivity, particularly in nucleophilic substitution reactions. The presence of the bromine atom makes it a potent alkylating agent, which is useful in various synthetic pathways. However, this also contributes to its corrosive and lachrymatory nature.

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Main Applications

Methyl Bromoacetate is predominantly used in organic synthesis, where it serves as an intermediate in the production of pharmaceuticals and agrochemicals. It is also employed in the synthesis of dyes, fragrances, and other fine chemicals. In the pharmaceutical industry, it is used to create active pharmaceutical ingredients (APIs) and other drug intermediates. Its role in agrochemicals includes the synthesis of herbicides and pesticides, contributing to crop protection and yield improvement.

Safety and Storage

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Due to its toxic and corrosive nature, Methyl Bromoacetate requires careful handling. It can cause severe skin and eye irritation and is harmful if inhaled or ingested. Proper personal protective equipment (PPE), including gloves, goggles, and respirators, is essential when working with this compound. Storage should be in a cool, dry, well-ventilated area, away from heat sources and open flames. Containers must be tightly sealed to prevent leakage and exposure to moisture, which can degrade the compound.

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B2B Procurement Guide

When procuring Methyl Bromoacetate, it is crucial to verify the supplier's credentials and the quality of the product. Request a Material Safety Data Sheet (MSDS) and certificates of analysis to ensure compliance with safety and purity standards. Consider factors such as purity levels, packaging options, and delivery terms. Bulk purchases may offer cost advantages, but ensure proper storage facilities are available to maintain the compound's integrity.

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