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Methyl 4-methoxy-2-naphthoate

Updated: 2026-07-15

Overview

Methyl 4-methoxy-2-naphthoate is an organic compound primarily used as an intermediate in pharmaceutical and chemical synthesis. It is derived from naphthalene and features a methoxy group and a methyl ester functional group. This compound is valued for its role in producing more complex molecules in medicinal chemistry and research. Its synthesis typically involves esterification and methoxylation reactions, often starting from 2-naphthoic acid derivatives. The compound's stability and solubility in organic solvents make it suitable for various laboratory and industrial applications.

Physical and Chemical Properties

4-乙氧基苯乙酮 CAS:1676-63-7 2-溴-5-甲氧基甲苯 27060-75-9 可分装湖北贝诺福化学科技有限公司

Methyl 4-methoxy-2-naphthoate appears as a white to off-white crystalline powder with a molecular weight of 216.23 g/mol. It has a melting point of approximately 80-85°C and is soluble in common organic solvents such as ethanol, acetone, and dichloromethane, but insoluble in water. The compound is stable under normal storage conditions but should be protected from prolonged exposure to light and moisture to prevent degradation. Its chemical structure includes a naphthalene ring system substituted with a methoxy group at the 4-position and a methyl ester at the 2-position, contributing to its reactivity in further chemical transformations.

Main Applications

Methyl 4-methoxy-2-naphthoate is primarily used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It serves as a building block for more complex molecules, particularly in the development of drugs targeting inflammation, cancer, and other medical conditions. In research settings, this compound is employed in organic synthesis to explore new chemical reactions and pathways. Its versatility and relatively straightforward synthesis make it a valuable tool for chemists working on drug discovery and material science projects.

Safety and Storage

4,4-二溴联苯 92-86-4 4,4-联苯二甲酸 787-70-2 4,4'-亚联苯基二异丁烯酸酯 13082-48-9 CAS 1198395-24-2湖北楚岳邦新材料科技有限公司

When handling Methyl 4-methoxy-2-naphthoate, appropriate safety measures should be taken to avoid inhalation, ingestion, or skin contact. Personal protective equipment (PPE) such as gloves, goggles, and lab coats are recommended. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are essential to maintain its stability. In case of accidental exposure, rinse affected areas with water and seek medical advice if necessary. Always refer to the material safety data sheet (MSDS) for detailed safety information.

B2B Procurement Guide

For B2B buyers, sourcing Methyl 4-methoxy-2-naphthoate requires attention to purity levels, supplier reliability, and pricing. High-purity grades (≥98%) are typically preferred for pharmaceutical applications, while lower grades may suffice for general research. Consider purchasing in bulk to reduce costs, but ensure proper storage conditions are maintained. Verify supplier credentials and request certificates of analysis (CoA) to confirm product specifications. Prices commonly range between $50-$100 per gram, depending on quantity and supplier. Establish long-term relationships with reputable suppliers to ensure consistent quality and availability.

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