Overview
Methyl 4-hydroxynicotinate is an organic compound derived from nicotinic acid. It is primarily used as an intermediate in pharmaceutical synthesis and chemical research. The compound is known for its stability and solubility in organic solvents, making it a versatile reagent in various applications. Its molecular structure includes a hydroxyl group and an ester functional group, which contribute to its reactivity and utility in synthetic chemistry. The compound is typically supplied as a white to off-white crystalline powder.
Physical and Chemical Properties
Methyl 4-hydroxynicotinate is a stable compound under normal conditions. It is soluble in organic solvents such as methanol and ethanol but has limited solubility in water. The exact melting and boiling points are not well-documented, but it is known to degrade under extreme temperatures or exposure to strong acids or bases. The compound's molecular weight is 153.14 g/mol, and its molecular formula is C7H7NO3. Its key chemical properties include reactivity with nucleophiles and electrophiles, making it useful in various synthetic pathways.
Main Applications
Methyl 4-hydroxynicotinate is primarily used in the pharmaceutical industry as an intermediate for the synthesis of active pharmaceutical ingredients (APIs). It is also employed in organic chemistry research for the development of new compounds and materials. In addition to pharmaceuticals, the compound finds applications in agrochemicals and specialty chemicals. Its versatility and reactivity make it a valuable building block in synthetic chemistry.
Safety and Storage
Proper handling of methyl 4-hydroxynicotinate is essential to ensure safety. The compound should be stored in a cool, dry place away from light and moisture to prevent degradation. Use protective equipment such as gloves and goggles when handling the material. Avoid inhalation or direct contact with skin or eyes. In case of exposure, rinse thoroughly with water and seek medical attention if necessary. Dispose of the compound in accordance with local regulations.
B2B Procurement Guide
When procuring methyl 4-hydroxynicotinate, it is important to verify the purity and quality of the product. Reputable suppliers should provide certificates of analysis (CoA) to confirm the compound's specifications. Consider the supplier's reputation, delivery times, and pricing. Bulk purchases may offer cost savings, but ensure proper storage conditions are maintained. Always check for compliance with relevant regulatory standards.
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