Methyl 3-amino-4-methoxybenzoate

Updated: 2026-08-04

Overview

2,4-Dichlorophenoxyacetic Acid (2,4-D) is a synthetic auxin herbicide first developed in the 1940s and remains one of the most widely used herbicides globally. As a chlorophenoxy compound, it mimics natural plant hormones to disrupt growth processes in susceptible plants. The chemical's selective action makes it particularly valuable in cereal crops and grass management, where it controls broadleaf weeds without harming monocotyledonous plants. Its effectiveness, relatively low cost, and established use history have maintained its position as a cornerstone herbicide in integrated weed management systems.

Physical and Chemical Properties

2,4-D appears as a white to yellow crystalline powder with a mild phenolic odor. It has moderate solubility in water (900 mg/L at 25°C) but dissolves readily in many organic solvents including alcohols, ketones, and ethers. The compound is stable under normal conditions but may decompose when heated, releasing toxic fumes of hydrogen chloride and other chlorinated compounds. Chemically, 2,4-D is a weak organic acid (pKa = 2.73) that forms water-soluble salts with bases. These salt formulations are often preferred for agricultural applications due to their improved solubility and handling characteristics compared to the acid form.

Main Applications

The primary use of 2,4-D is as a selective herbicide in agriculture, particularly in cereal crops (wheat, corn, rice), sugarcane, and pasture management. It effectively controls many broadleaf weeds while leaving grasses largely unaffected. In forestry, it's used for brush control and conifer release programs. Beyond herbicidal uses, 2,4-D finds application as a plant growth regulator in fruit production to prevent premature fruit drop. Research laboratories utilize it for plant tissue culture and physiological studies. Some specialized formulations are employed in aquatic weed control and right-of-way vegetation management.

Safety and Storage

2,4-D requires careful handling as it can cause skin and eye irritation, and may be harmful if inhaled or swallowed. Personal protective equipment including gloves, goggles, and respiratory protection should be used when handling the concentrated form. The compound is moderately persistent in soil (half-life 7-10 days) and can contaminate water sources if improperly applied. Storage should be in original, tightly sealed containers away from heat, sparks, and open flame. Incompatible materials include strong oxidizers and alkaline substances. Secondary containment is recommended to prevent environmental contamination in case of leaks or spills.

B2B Procurement Guide

Industrial buyers should specify the required formulation (acid, amine salt, or ester) and purity level based on intended application. Technical grade (95-98% purity) is common for formulation purposes, while analytical grade (≥99%) is needed for research applications. Consider regulatory status in target markets - 2,4-D approvals vary by country and some formulations may be restricted. Bulk purchasers should evaluate transportation options (typically in 25kg bags or 200kg drums) and storage capacity. Establish quality control parameters including assay, moisture content, and impurity levels.