Methoxynicotinic Acid

Updated: 2026-07-15

Overview

Methoxynicotinic acid, also known as 3-methoxynicotinic acid, is an organic compound derived from nicotinic acid. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound features a methoxy group attached to the pyridine ring, which influences its reactivity and solubility properties. Due to its structural similarity to nicotinic acid, methoxynicotinic acid is often utilized in research and industrial applications where modified pyridine derivatives are required. Its synthesis typically involves the methoxylation of nicotinic acid or its derivatives under controlled conditions.

Physical and Chemical Properties

Methoxynicotinic acid appears as a white to off-white crystalline powder with a melting point ranging between 180-185°C. It is soluble in common organic solvents such as methanol and ethanol but exhibits limited solubility in water. The compound is stable under normal storage conditions but may degrade when exposed to excessive heat or prolonged light exposure. The molecular formula of methoxynicotinic acid is C7H7NO3, with a molecular weight of 153.14 g/mol. Its chemical structure includes a pyridine ring substituted with a methoxy group and a carboxylic acid functional group, which contributes to its reactivity in synthetic applications.

Main Applications

Methoxynicotinic acid serves as a key intermediate in the pharmaceutical industry, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals. Its derivatives are explored for potential therapeutic applications, including antimicrobial and anti-inflammatory agents. In agrochemicals, methoxynicotinic acid is used to formulate pesticides and herbicides. Its structural properties allow for the development of compounds that target specific plant or pest biochemical pathways. Research continues to explore its potential in other industrial applications, such as materials science and specialty coatings.

Safety and Storage

Methoxynicotinic acid should be handled with care to avoid skin contact, inhalation, or ingestion. Personal protective equipment (PPE), including gloves and safety goggles, is recommended during handling. In case of exposure, rinse affected areas thoroughly with water and seek medical attention if necessary. The compound should be stored in a tightly sealed container in a cool, dry place, away from direct sunlight and moisture. Proper storage conditions help maintain its stability and prevent degradation. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety and handling instructions.

B2B Procurement Guide

When procuring methoxynicotinic acid, B2B buyers should prioritize suppliers with verified quality certifications, such as ISO or GMP compliance. Request certificates of analysis (CoA) to confirm purity and composition. Transparency in sourcing and manufacturing processes is critical for ensuring product consistency. Price ranges vary depending on purity levels and order quantities. Bulk purchases may offer cost advantages, but buyers should balance cost considerations with quality assurance. Establish clear communication with suppliers regarding lead times, packaging options, and logistics to streamline procurement processes.