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Methoxyacetic hydrazide

Updated: 2026-07-21

Overview

Methoxyacetohydrazide is a specialized chemical compound primarily used as an intermediate in pharmaceutical synthesis and organic chemistry. Its molecular structure includes a methoxy group attached to an acetohydrazide moiety, making it useful for various chemical reactions. The compound is known for its stability and solubility in water and polar solvents, which enhances its versatility in industrial applications. Due to its role in synthesizing more complex molecules, methoxyacetohydrazide is often sourced by pharmaceutical companies and research institutions. Proper handling and storage are essential to maintain its chemical integrity and ensure safety in the workplace.

Physical and Chemical Properties

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Methoxyacetohydrazide typically presents as a white to off-white crystalline powder with a molecular weight of 104.11 g/mol. It has a melting point range of approximately 110-115°C, indicating moderate thermal stability. The compound is soluble in water and common polar organic solvents, which facilitates its use in liquid-phase reactions. Key chemical properties include its reactivity as a hydrazide derivative, enabling it to participate in condensation and nucleophilic substitution reactions. These characteristics make it valuable for constructing heterocyclic compounds and other pharmacologically active molecules.

Main Applications

The primary use of methoxyacetohydrazide is in the pharmaceutical industry, where it serves as a building block for active pharmaceutical ingredients (APIs). It is particularly useful in the synthesis of hydrazone derivatives and other nitrogen-containing compounds. Additionally, researchers employ it in organic synthesis to develop novel molecules with potential therapeutic effects. Beyond pharmaceuticals, methoxyacetohydrazide finds limited use in agrochemicals and specialty chemicals. Its role in these sectors is niche but growing, driven by the demand for innovative chemical intermediates.

Safety and Storage

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Handling methoxyacetohydrazide requires adherence to standard laboratory safety protocols. Personal protective equipment (PPE), including gloves and goggles, is mandatory to prevent skin contact or inhalation. The compound should be stored in a cool, dry environment, away from incompatible substances such as strong oxidizers. In case of accidental exposure, immediate measures such as rinsing with water (for skin contact) or seeking fresh air (for inhalation) are recommended. Proper disposal methods must comply with local regulations to minimize environmental impact.

B2B Procurement Guide

Procuring methoxyacetohydrazide involves evaluating suppliers for reliability, purity guarantees, and compliance with industry standards. Buyers should request certificates of analysis (CoA) to verify the compound's specifications, including purity and moisture content. Bulk purchases may qualify for discounts, but storage capacity and shelf life should be considered. It is advisable to establish long-term relationships with reputable suppliers to ensure consistent quality and availability. Comparing prices and lead times across multiple vendors can help optimize procurement costs without compromising on quality.

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