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Methanol, anhydrous

Updated: 2026-08-03

Overview

Anhydrous methanol reagent is a high-purity form of methanol with minimal water content, typically less than 0.1%. It is a versatile solvent and reagent used in various industrial and laboratory applications. Methanol is one of the simplest alcohols and is often utilized in organic synthesis, chromatography, and as a fuel additive. Due to its hygroscopic nature, anhydrous methanol must be handled and stored carefully to maintain its purity. It is commonly available in bulk quantities for industrial use and smaller laboratory-grade bottles for research purposes.

Physical and Chemical Properties

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Anhydrous methanol is a colorless, volatile liquid with a characteristic alcoholic odor. It has a low viscosity and evaporates quickly at room temperature. The compound is highly soluble in water and most organic solvents, making it an excellent solvent for many chemical reactions. Methanol is flammable and burns with a nearly invisible flame, which poses a significant safety hazard. It also has a relatively low boiling point and melting point, which are critical considerations for storage and handling. The density of methanol is lower than water, and it forms azeotropes with several compounds.

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Main Applications

Anhydrous methanol is widely used as a solvent in the pharmaceutical and chemical industries. It serves as a key ingredient in the production of formaldehyde, acetic acid, and other important chemicals. In laboratories, it is used for HPLC (High-Performance Liquid Chromatography) and as a mobile phase in analytical chemistry. Methanol is also utilized as an antifreeze in automotive applications and as a denaturant for ethanol. Additionally, it is a component in biodiesel production and as a fuel in racing cars and model engines due to its high octane rating.

Safety and Storage

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Anhydrous methanol is highly toxic and can cause severe health effects if ingested, inhaled, or absorbed through the skin. Exposure can lead to blindness, organ damage, or even death. Proper personal protective equipment (PPE), such as gloves, goggles, and respirators, should always be used when handling this chemical. Storage should be in tightly sealed containers made of materials compatible with methanol, such as stainless steel or certain plastics. The storage area must be well-ventilated, away from heat sources, and equipped with fire suppression systems. Spills should be cleaned up immediately using appropriate absorbents.

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B2B Procurement Guide

When procuring anhydrous methanol reagent, B2B buyers should prioritize suppliers who provide detailed certificates of analysis (CoA) to verify purity and quality. Bulk purchases typically offer cost savings, but storage capacity and shelf-life considerations must be evaluated. It is advisable to establish long-term relationships with reputable suppliers to ensure consistent quality and reliable delivery. Buyers should also confirm that the supplier complies with all relevant safety and environmental regulations. Transportation of methanol requires hazardous material handling certifications and proper labeling.

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