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Manuka Extract

Updated: 2026-07-22

Overview

Stachys Sieboldii Extract is derived from the tuberous roots of Stachys affinis, commonly known as Chinese artichoke or crosne. Traditionally used in East Asian herbal medicine, it has gained attention in modern phytopharmaceuticals for its bioactive compounds. The extract is rich in stachyose (a prebiotic oligosaccharide), phenolic acids, and flavonoids, contributing to its therapeutic potential. Commercial production typically involves water or ethanol extraction followed by spray drying to obtain powder forms. Standardized extracts often specify stachyose content (commonly 20–50%) as a marker compound. Its cultivation is concentrated in China, Japan, and France, with extraction facilities adhering to Good Manufacturing Practice (GMP) standards for botanical products.

Physical and Chemical Properties

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The extract exhibits hygroscopic properties due to its high polysaccharide content, requiring careful moisture control during storage. Analytical characterization typically reveals UV absorption peaks at 280 nm (phenolics) and 320 nm (flavonoids). pH of 1% aqueous solution ranges from 5.5 to 6.5, indicating mild acidity. Key functional groups include hydroxyl (–OH) from carbohydrates and phenolic compounds, confirmed by FTIR spectroscopy. The extract shows stability at temperatures below 60°C, beyond which thermal degradation of active components may occur. Particle size distribution for powdered forms typically ranges between 80–200 mesh for optimal solubility in formulations.

Main Applications

In nutraceuticals, the extract is formulated into gut health supplements leveraging its prebiotic stachyose content, which selectively promotes bifidobacteria growth. Pharmaceutical applications include adjuvant therapy for diabetes management, supported by clinical studies showing hypoglycemic effects through α-glucosidase inhibition. The food industry incorporates it into functional beverages and dairy products as a natural sweetener alternative (30–50% sweetness of sucrose). Cosmetic formulations utilize its antioxidant properties in anti-aging serums, typically at 0.5–2% concentration. Emerging research explores its potential in animal feed to improve livestock intestinal microbiota.

Safety and Storage

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Acute toxicity studies (LD50 > 5000 mg/kg in rats) classify the extract as low-risk. However, excessive consumption may cause mild gastrointestinal discomfort due to its high fiber content. Regulatory status varies by region: approved as a food ingredient in China (GB 2760) and the EU Novel Food Catalogue, while FDA regulates it as a dietary supplement component. Long-term storage requires oxygen-impermeable packaging with desiccants to prevent clumping. Shelf life is typically 24 months when stored properly. Quality deterioration indicators include color darkening (oxidation) and moisture absorption exceeding 5%. Cold chain logistics are recommended for bulk transport to tropical climates.

B2B Procurement Guide

Industrial buyers should prioritize suppliers providing: 1) Certificate of Analysis (CoA) with stachyose quantification, 2) residual solvent reports (if ethanol-extracted), and 3) heavy metal testing results (lead < 2 ppm, arsenic < 1 ppm). Minimum order quantities (MOQs) for powder extracts commonly start at 25 kg, with price breaks at 100 kg+ volumes. Technical specifications should confirm absence of synthetic additives and irradiation treatment. Audit reports for GMP or ISO 22000 certification add credibility. For OEM formulations, request pilot-scale compatibility testing with your base products. Payment terms often include 30% deposit with balance before shipment, especially for international transactions.

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