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Mannobiose

Updated: 2026-07-15

Overview

Mannobiose is a disaccharide consisting of two mannose units linked by a β(1→4) glycosidic bond. It is naturally found in some plants and microbial polysaccharides. Due to its unique structure, mannobiose is used in various industrial applications, particularly in the food and pharmaceutical sectors. As a non-reducing sugar, mannobiose is chemically stable and does not participate in Maillard reactions, making it suitable for products requiring long shelf life. Its sweet taste and low caloric content also make it an attractive alternative to traditional sweeteners in certain applications.

Physical and Chemical Properties

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Mannobiose appears as a white crystalline powder with a sweet taste. It has a molecular weight of 342.30 g/mol and is soluble in water but only slightly soluble in ethanol. The compound is stable under normal conditions but may degrade at high temperatures or in acidic environments. Its melting point ranges between 180-185°C, and it does not have a distinct boiling point due to decomposition before reaching boiling. The sugar's non-reducing nature makes it less reactive compared to reducing sugars, which is beneficial for stability in formulated products.

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Main Applications

In the food industry, mannobiose is used as a low-calorie sweetener and a prebiotic to promote beneficial gut bacteria. Its stability and sweetening properties make it suitable for functional foods and dietary supplements. In pharmaceuticals, mannobiose serves as an excipient in tablet formulations and as a component in diagnostic reagents. Research also explores its potential in drug delivery systems due to its biocompatibility and ability to interact with biological receptors.

Safety and Storage

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Mannobiose is generally recognized as safe (GRAS) for consumption. However, proper handling is recommended to avoid inhalation or direct contact with skin and eyes. It should be stored in a cool, dry place, protected from moisture and direct sunlight to maintain its stability. In industrial settings, workers should use appropriate personal protective equipment (PPE) such as gloves and masks when handling large quantities to minimize exposure risks.

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B2B Procurement Guide

When procuring mannobiose, businesses should prioritize suppliers that provide certificates of analysis (CoA) to verify purity and quality. Bulk purchases often come with cost advantages, so negotiating long-term contracts can be beneficial. It is also advisable to assess supplier reliability, lead times, and compliance with industry standards such as ISO or GMP. For specialized applications, custom purity grades or packaging options may be available upon request.

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