Lysyl group
Overview
The lysyl group is a functional moiety derived from lysine, an essential amino acid. It plays a critical role in biochemical pathways, particularly in post-translational modifications of proteins. Its reactive primary amine group enables participation in crosslinking reactions, making it valuable in both industrial and research settings. In nature, the lysyl group is integral to collagen formation and enzyme function. Synthetically, it is utilized to modify peptides and proteins for enhanced stability or targeted delivery in pharmaceuticals.
Physical and Chemical Properties
The lysyl group consists of a six-carbon chain with a terminal amine group, giving it basic properties. It is highly soluble in water due to its polar nature, facilitating its use in aqueous biochemical reactions. The group’s reactivity is primarily attributed to the nucleophilic amine, which forms bonds with carbonyl groups or other electrophiles. Under standard conditions, it is stable but should be protected from strong oxidizers. Its molecular weight (129.18 g/mol) and structure allow for easy integration into larger molecules, such as peptides or synthetic polymers.
Main Applications
In the pharmaceutical industry, the lysyl group is used to conjugate drugs to proteins, improving bioavailability or targeting specific tissues. For example, lysyl-modified insulin analogs exhibit prolonged action. It also serves as a crosslinker in hydrogel formulations for drug delivery. In food science, lysyl groups fortify proteins to enhance nutritional value or texture. Industrial applications include enzyme stabilization and biodegradable polymer synthesis, leveraging its reactive sites for polymerization.
Safety and Storage
While not highly toxic, the lysyl group requires careful handling to avoid irritation. Use gloves and goggles when working with concentrated forms. Storage should be in airtight containers under inert conditions to prevent degradation or unwanted reactions with moisture or oxygen. Disposal must comply with local chemical waste regulations. Suppliers typically provide Safety Data Sheets (SDS) with detailed hazard and first-aid measures for bulk quantities.
B2B Procurement Guide
B2B buyers should prioritize suppliers with ISO or GMP certifications to ensure quality. Key specifications include purity (e.g., >95% for research-grade) and form (liquid, solid, or derivative). Bulk pricing is often negotiable for orders exceeding 1 kg. Request batch-specific COAs (Certificates of Analysis) and confirm stability data for long-term storage. For specialized applications (e.g., GMP-compliant pharmaceuticals), opt for vendors with documented regulatory compliance.
Related Manufacturers
- 主营：架桥剂、YW100 锂萃取剂、苯乙烯磷酸、端羧基液体丁腈橡胶、10-羟基癸酸、乙烯基磷酸二乙酯、1-乙炔基环已醇、肉豆蔻酸镁、硬脂酸钴、全氟三丁胺、磷酸锰铁锂、β-磷酸三钙、十一烯酸、钨酸铝、间二异丙苯、锂硅合金、溴甲酚绿、生物活性玻璃、溴代海因树脂颗粒、红铝、龙涎酮、原丁酸三甲酯
- 主营：乙酰基赖氨酸、ELISA试剂盒、PCR试剂盒、科研试剂
- 主营：阻燃剂、乙酸镍、乙酸镝、氟苯基、羟乙基、硫酸锂、硫酸锶、溴氨酸、香茅醇、肌氨酸、锂电池、四氢萘、磷酸铬、肉桂醇、碳酸镁、碳酸镍、防冻剂、磷酸铝、叔丁醇、浮选剂、稀释剂、去除剂、庚二酸、除磷剂、十八烯
- 主营：DMF、DMAC、二丙酮醇、四甲基胍、马来酸酐、丙二醇、乙二醇、甲酸、甲醇、十二醇、柠檬酸、己二醇、甘油、四氢呋喃、碳酸丙烯酯、吐温、无水氯化钙、乙酸乙酯、氢氧化钠、二乙醇胺、司盘、过硫酸钠、氧化钙、氯化钾
- 主营：生物素修饰蛋白、fitc标记蛋白、聚苯乙烯微球、聚赖氨酸、pvc微球、嵌段共聚物、生物素标记、荧光标记、纳米颗粒、核苷糖、aie、复合微球、功能化载玻片、荧光染料、金属配合物、Mxene、介孔二氧化硅微球、磁性纳米颗粒、小分子PEG、聚合物、纳米金、聚合物微球、荧光微球、荧光探针、点击化学、小分子
- 主营：化学试剂、氯金酸、卡尔费休、三氟乙酰基、乙醇、异丙醇、药用辅料、依地酸钙钠、碳酸钠、盐酸氨丁三醇、龙胆酸、枸橼酸钠、甲醇、氢氧化钠、钴锰催化剂、硫酸锰、乙腈、色谱试剂、助剂、指示剂、醋酸锰、醋酸钴、氨丁三醇、尿素、硼酸
- 主营：酵母浸粉、甜菜碱、氯化胆碱、D-氨基葡萄糖盐酸盐、乙基纤维素、酪蛋白酸钠 酪朊酸钠、酪蛋白 干酪素、壳寡糖、壳聚糖、聚维酮K30、卡波姆、聚丙烯酸钠、结冷胶、黄原胶、海藻酸钠、果胶、瓜尔豆胶 瓜尔胶
- 主营：氯化胆碱、甜菜碱、酵母浸粉、赖氨酸、氨基丁酸、羟丙基纤维素、甘露寡糖、D-异抗坏血酸钠、阿拉伯胶、海藻酸钠、黄原胶、甘氨酸、色氨酸、脯氨酸、聚谷氨酸、水解角蛋白、氨糖、阿洛酮糖、甘露糖、环糊精、刺云实胶、聚维酮k30、丁二酸、己二酸
- 主营：β-环状糊精、阿拉伯胶、刺槐豆胶、瓜尔豆胶、果胶、海藻酸丙二醇酯、海藻酸钠、黄原胶、结冷胶、聚丙烯酸钠、卡波姆、卡拉胶、魔芋粉、塔拉胶、沙蒿籽胶、明胶、温轮胶、大豆分离蛋白、低聚半乳糖、菊粉、水苏糖、罗汉果甜苷、木聚糖、索马甜、氨糖
- 主营：阿斯巴甜、赤藓糖醇、菊粉、辛烯基琥珀酸淀粉钠、结晶果糖、甜菊糖、海藻糖、大豆低聚糖、阿拉伯胶、刺槐豆胶、瓜尔豆胶、果胶、黄原胶、结冷胶、聚丙烯酸钠、抗性糊精、可得然胶、魔芋粉、塔拉胶、琼脂、沙蒿籽胶、明胶、温轮胶、亚麻籽胶、大豆蛋白粉
- 主营：低聚果糖、低聚木糖、甘露寡糖、菊粉、麦芽糖醇、木糖醇、纽甜、乳糖、乳糖醇、三氯蔗糖、聚葡萄糖、索马甜、瓜尔豆胶、果胶、海藻酸丙二醇酯、海藻酸钠、黄原胶、卡拉胶、可得然胶、大豆多糖、魔芋粉、塔拉胶、琼脂、沙蒿籽胶、明胶
- 主营：复合维生素、阿拉伯胶、刺槐豆胶、结冷胶 低酰基结冷胶、羧甲基纤维素钠、乙基纤维素、D-氨基葡萄糖盐酸盐、瓜尔豆胶 瓜尔胶、果胶、海藻酸钠、黄原胶、聚丙烯酸钠、卡波姆、卡拉胶、可得然胶、魔芋粉、琼脂 琼脂粉、明胶、温轮胶 威兰胶、聚维酮K30、壳聚糖、壳寡糖、酪蛋白 干酪素
- 主营：木糖醇、麦芽糖醇、赤藓糖醇、羧甲基纤维素钠、低聚果糖、低聚木糖、水苏糖、乳糖、菊粉、阿拉伯糖、核糖、甘露糖醇、纽甜、三氯蔗糖、瓜尔胶、黄原胶、海藻酸钠、酪蛋白酸钠、琼脂粉、魔芋粉、聚丙烯酸钠、魔芋胶、结冷胶、卡拉胶、植酸钠
- 主营：酶cγ链、α2巨球、素d合成、纤连蛋白、抗组蛋白、肌醇抗体、蛋白样环、敏感蛋白、牛骨钙素、蛋白重链、金属肽酶、乳球蛋白、钩端螺旋、蛋白激酶、高血糖素、钙调蛋白、小鼠α1抗、ELISA试剂盒、pcr检测试剂、生化检测试剂
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、关基因、脂蛋白、亲环素、钾通道、列抗体、ntp溶液、蛋白酶、脑蛋白、病毒抗、蛋白质、239抗体、dtt溶液、科研试剂